2-Coumarate reductase

In enzymology, a 2-coumarate reductase or melilotate dehydrogenase  is an enzyme that catalyzes the chemical reaction


 * 3-(2-hydroxyphenyl)propanoate + NAD+ $$\rightleftharpoons$$ 2-coumarate + NADH + H+

Thus, the two substrates of this enzyme are 3-(2-hydroxyphenyl)propanoate and NAD+, whereas its 3 products are 2-coumarate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-(2-hydroxyphenyl)propanoate:NAD+ oxidoreductase. This enzyme participates in phenylalanine metabolism.