2020–21 Super League Greece 2

The 2020–21 Super League 2 was the second season of the Super League 2, the second-tier Greek professional league for association football clubs, since restructuring of the Greek football league system.

Season's start has been delayed due to the COVID-19 second lockdown in Greece that began in November 2020 and started on 16 January 2021.

Team changes
The following teams have changed division since the 2019–20 season.

To Super League Greece 2
Promoted from Gamma Ethniki
 * Diagoras Rodos
 * Ierapetra
 * Ionikos
 * Trikala

Relegated from Super League
 * Xanthi

From Super League Greece 2
Promoted to Super League
 * Apollon Smyrnis
 * PAS Giannina

Relegated to Football League
 * Apollon Pontus

Relegated to Gamma Ethniki
 * Kerkyra
 * Platanias

Teams
The following 12 clubs are competing in the Super League 2 during the 2020–21 season.

Play-off round
The top six teams from Regular season will meet once (5 matches per team) for places in 2021–22 Super League Greece as well as deciding the league champion.