2021–22 St. John's Red Storm men's basketball team

The 2021–22 St. John's Red Storm men's basketball team represented St. John's University during the 2021–22 NCAA Division I men's basketball season. They were coached by Mike Anderson, in his third year at the school, and played their home games at Carnesecca Arena and Madison Square Garden as members of the Big East Conference.

Previous season
The Red Storm finished the season 16–11, 10–9 in Big East play to finish in a tie for fourth place. As the No. 4 seed in the Big East tournament, they lost to Seton Hall in the quarterfinals.

Schedule and results
!colspan=12 style=| Exhibition

!colspan=12 style=| Non-conference regular season

!colspan=12 style=| Big East regular season

!colspan=12 style=|Big East tournament

Rankings

 * No rankings released

All-Big East First Team

 * Julian Champagnie

All-Big East Honorable Mention

 * Posh Alexander

Source