2021 Colorado Buffaloes football team

The 2021 Colorado Buffaloes football team represented the University of Colorado Boulder during the 2021 NCAA Division I FBS football season. The Buffaloes were led by second-year head coach Karl Dorrell. They played their home games on campus at Folsom Field as a member of the South Division of the Pac-12 Conference.

Coaching staff

 * William Vlachos took over as the offensive line coach when Rodrigue was fired