2021 Internationaux de Tennis de Vendée – Doubles

Jonny O'Mara and Ken Skupski were the defending champions but only O'Mara chose to defend his title, partnering Treat Huey. O'Mara lost in the first round to Antoine Hoang and Kyrian Jacquet.

Jonathan Eysseric and Quentin Halys won the title after defeating David Pel and Aisam-ul-Haq Qureshi 4–6, 7–6(7–5), [10–8] in the final.

Seeds
• # David Pel / 🇵🇰 Aisam-ul-Haq Qureshi (final)

• # Romain Arneodo /  Hugo Nys (quarterfinals)

• # 🇺🇸 Nathaniel Lammons / 🇦🇺 Matt Reid (semifinals)

• # Treat Huey / 🇬🇧 Jonny O'Mara (first round)