2021 Internazionali di Tennis Città di Perugia – Doubles

Tomislav Brkić and Ante Pavić were the defending champions but chose not to defend their title.

Vitaliy Sachko and Dominic Stricker won the title after defeating Tomás Martín Etcheverry and Renzo Olivo 6–3, 5–7, [10–8] in the final.

Seeds
• # 🇮🇹 Salvatore Caruso / 🇮🇹 Federico Gaio (semifinals)

• # Ruben Gonzales / 🇺🇸 Hunter Johnson (first round)

• # Mark Vervoort / 🇧🇴 Federico Zeballos (quarterfinals, withdrew)

• # Nuno Borges /  Francisco Cabral (first round, withdrew)