2021 Internazionali di Tennis Città di Perugia

The 2021 Internazionali di Tennis Città di Perugia was a professional tennis tournament played on clay courts. It was the sixth edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Perugia, Italy between 5 and 11 July 2021.

Seeds

 * 1 Rankings are as of 28 June 2021.

Other entrants
The following players received wildcards into the singles main draw:
 * 🇮🇹 Flavio Cobolli
 * 🇮🇹 Francesco Forti
 * 🇮🇹 Luca Vanni

The following players received entry from the qualifying draw:
 * 🇧🇦 Nerman Fatić
 * 🇮🇹 Francesco Passaro
 * 🇰🇿 Timofey Skatov
 * 🇮🇹 Giulio Zeppieri

Singles

 * 🇦🇷 Tomás Martín Etcheverry def. 🇺🇦 Vitaliy Sachko 7–5, 6–2.

Doubles

 * 🇺🇦 Vitaliy Sachko / Dominic Stricker def. 🇦🇷 Tomás Martín Etcheverry / 🇦🇷 Renzo Olivo 6–3, 5–7, [10–8].