2022–23 R.S.C. Anderlecht season

The 2022–23 season was the 115th season in the history of R.S.C. Anderlecht and their 87th consecutive season in the top flight. The club participated in the Belgian Pro League, the Belgian Cup, and the UEFA Europa Conference League.

Matches
The league fixtures were announced on 22 June 2022.

Third qualifying round
The draw for the third qualifying round was held on 18 July 2022.

Play-off round
The draw for the play-off round was held on 2 August 2022.

Group stage
The draw for the group stage was held on 26 August 2022.

Knockout round play-offs
The knockout round play-offs draw was held on 7 November 2022.

Round of 16
The knockout round play-offs draw was held on 24 February 2023.

Appearances and goals
! colspan=14 style=background:#dcdcdc; text-align:center| Goalkeepers

! colspan=14 style=background:#dcdcdc; text-align:center| Defenders

! colspan=14 style=background:#dcdcdc; text-align:center| Midfielders

! colspan=14 style=background:#dcdcdc; text-align:center| Forwards

! colspan=14 style=background:#dcdcdc; text-align:center| Players transferred out during the season