Chondroitin AC lyase

The enzyme chondroitin AC lyase catalyzes the chemical reaction


 * Eliminative degradation of polysaccharides containing 1,4-β- D -hexosaminyl and 1,3-β- D -glucuronosyl linkages to disaccharides containing 4-deoxy-β- D -gluc-4-enuronosyl groups

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is chondroitin AC lyase. Other names in common use include chondroitinase (ambiguous), chondroitin sulfate lyase, chondroitin AC eliminase, chondroitin AC lyase, chondroitinase AC, and ChnAC.

Structural studies
As of late 2007, 11 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , , , , , and.