Gluconate dehydratase

The enzyme gluconate dehydratase catalyzes the chemical reaction


 * D -gluconate $$\rightleftharpoons$$ 2-dehydro-3-deoxy- D -gluconate + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is  D -gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming). Other names in common use include  D -gluconate dehydratase, and  D -gluconate hydro-lyase. This enzyme participates in the pentose phosphate pathway.

Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code.