Mannonate dehydratase

The enzyme mannonate dehydratase catalyzes the chemical reaction


 * D -mannonate $$\rightleftharpoons$$ 2-dehydro-3-deoxy- D -gluconate + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is  D -mannonate hydro-lyase (2-dehydro-3-deoxy- D -gluconate-forming). Other names in common use include mannonic hydrolase, mannonate hydrolyase, altronic hydro-lyase, altronate hydrolase,  D -mannonate hydrolyase, and  D -mannonate hydro-lyase. This enzyme participates in pentose and glucuronate interconversions.

Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code.