Phosphatidylinositol-3-phosphatase

The enzyme phosphatidylinositol-3-phosphatase (EC 3.1.3.64) catalyzes the reaction


 * 1-phosphatidyl-1 D -myo-inositol 3-phosphate + H2O $$\rightleftharpoons$$ 1-phosphatidyl-1 D -myo-inositol + phosphate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is 1-phosphatidyl-1 D -myo-inositol-3-phosphate 3-phosphohydrolase. Other names in common use include inositol-1,3-bisphosphate 3-phosphatase, inositol 1,3-bisphosphate phosphatase, inositol-polyphosphate 3-phosphatase,  D -myo-inositol-1,3-bisphosphate 3-phosphohydrolase, and phosphatidyl-3-phosphate 3-phosphohydrolase. This enzyme participates in inositol phosphate metabolism and phosphatidylinositol signaling system.

Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and.