Talk:454 Life Sciences

Untitled
This article, while highly detailed and informative, reads like an advertisement. Especially the advantages and 'disadvantages' section. 128.252.206.9 (talk) 20:59, 19 November 2008 (UTC)

Agree entirely. At least a comparison to competitors (eg the color space ligation technology used in ABI SOLiD) would be useful. 129.176.171.5 19:10, 4 December 2008 (UTC) —Preceding unsigned comment added by 129.176.151.10 (talk)

I agree. Until someone writes "a comparison to competitors", we can rename the section as "Advantages" and make an empty section called "Competitive technologies" nickmeet (talk) 23:50, 5 February 2009 (UTC)

I deleted the Advantages and disadvantages section-it was basically an advertisement, and I do not think it could have been reworded to be encyclopedic. The article is excessively detailed-other sections should probably be condensed or deleted as they add little content of value Mynameisntbob1 (talk) 03:57, 13 October 2010 (UTC)


 * Good job, Mynameisntbob1! I will remove the advertisement tag now.--Biologos (talk) 10:47, 13 October 2010 (UTC)

Why is it called "454"
It may be helpful to clarify why "454" sequencing is called "454." Andrew73 (talk) 02:55, 6 September 2009 (UTC)

As someone who worked at a company that licenced/cooperated on some of the chemicals they used, the heresay is that it was named for the 454 "big block" v8 engine. I've got no citation other that "i was in conference room in the early 2000 and the founder told us" 20:58, 26 February 2018 (UTC)155.4.6.12 (talk)

Who invented 454 sequencing?
The link in the article under "History and Major Achievements" leads to a patent for a "Bioassay system including optical detection apparatuses, and method for detecting biomolecules" with only Taiwanese inventors.--Biologos (talk) 10:36, 14 October 2010 (UTC)

Applied Biosystems versus Roche Applied Science
In the field "See also" there is a link to information on "Applied Biosystems". However, in the article there is no hint to Applied Biosystems. Instead, the talk is about Roche Applied Science. Is this a misleading caused by the similar names or what is the intention for the link to Applied Biosystems? — Preceding unsigned comment added by 85.5.149.19 (talk) 02:05, 28 December 2012 (UTC)
 * I removed the link.--Biologos (talk) 08:56, 20 March 2013 (UTC)

Notability
Because of the recent deletion/redirection to Roche that I reverted: 454 is notable by itself, since "it has been the subject of significant coverage in reliable, independent secondary sources" (WP:CORP), as evidenced in the references section of the article (Wall Street Journal, New York Times, scientific journals). And: "Notability is not temporary: once a topic has been the subject of "significant coverage" in accordance with the general notability guideline, it does not need to have ongoing coverage." (WP:NTEMP)--Biologos (talk) 09:07, 20 March 2013 (UTC)

External links modified
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 * Added archive https://web.archive.org/web/20081217175926/http://www.eva.mpg.de/genetics/pdf/Green_Complete_Cell_2008.pdf to http://www.eva.mpg.de/genetics/pdf/Green_Complete_Cell_2008.pdf
 * Added tag to http://jimwatsonsequence.cshl.edu/cgi-perl/gbrowse/jwsequence/?name=Sequence:NM_005516.3

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