Talk:Brain metastasis

Wiki Education Foundation-supported course assignment
This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): A xi, Jocelyn.powell. Peer reviewers: Holly.calderon.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 16:11, 16 January 2022 (UTC)

Please do not merge article
While i appreciate your efforts to improve wikipedia,the free encyclopedia,i do not agree that this article should be merged into metastasis.I feel that brain metastases deserve a seperate article,and,given that their treatment differs greatly from that of the treatment of other sites of metastatic disease,as radiotherapy and surgery play a much bigger role in treatment,while chemotherapy is,in most cases,ineffective due to the blood brain barrier.So,please keep this article on wikipedia.Immunize (talk) 15:12, 12 January 2010 (UTC)
 * Note that currently Brain metastasis redirects to metastasis. However, if this article were properly cited with reliable sources it would have a greater chance of standing on its own. Regards, PDCook (talk) 15:24, 12 January 2010 (UTC)
 * I think that if this article is kept, it should be moved to Brain metastasis. I believe the title of most other medical articles is in the singular form. PDCook (talk) 15:59, 12 January 2010 (UTC)

I agree.Immunize (talk) 16:00, 12 January 2010 (UTC) does the fact that this article was catogorized as an oncology article just now improve it's chances of avoiding deletion?Immunize (talk) 16:03, 12 January 2010 (UTC)
 * Not really, categorization has nothing to do with merit. However, I strongly urge you to provide sources. Where did you get the article content from? Regards, PDCook (talk) 16:09, 12 January 2010 (UTC)

mostly emedicine neurology Immunize (talk) 18:22, 12 January 2010 (UTC)
 * Please review WP:Citing sources so you can properly cite the source you got this information from. If it was from a website, you can use this citation template. PDCook (talk) 18:41, 12 January 2010 (UTC)

I am very new to wikipedia.i still have difficulty citing references.Please keep this article until i or another contributer can add references.Immunize (talk) 19:06, 12 January 2010 (UTC)
 * The links I have provided should tell you everything you need to know about citing your sources. I highly recommend adding the references. If you have any questions, please ask (on my talk page). PDCook (talk) 19:08, 12 January 2010 (UTC)

Thank you.Immunize (talk) 16:00, 14 January 2010 (UTC)

Requested move

 * The following discussion is an archived discussion of a requested move. Please do not modify it. Subsequent comments should be made in a new section on the talk page. No further edits should be made to this section. 

The result of the move request was: page moved, histories merged.  Ron h jones (Talk) 20:46, 25 January 2010 (UTC)

Brain metastases → Brain metastasis — Most medical articles use the singular, not plural, form.—PDCook (talk) 15:01, 16 January 2010 (UTC)
 * Comment I think this is a speedy rename criterion you could have done. 76.66.197.17 (talk) 04:49, 17 January 2010 (UTC)
 * Possibly, but I didn't create the article nor am I interested in editing it anymore, so I figured I'd let others weigh in on it. PDCook (talk) 05:08, 17 January 2010 (UTC)


 * Oppose Just leave it as is. Our article on the process in general is currently at Metastasis, so I suppose that an argument could me made for internal consistency, but of the three references given one seems to prefer metastases, the other metastasis, and the other I have no idea why it's even a reference. There's just no compelling reason to change right now. — V = I * R (talk to Ohms law) 06:01, 20 January 2010 (UTC)
 * Support as no compelling reason has been given why this should not be singular per our normal naming conventions. Ucucha 03:09, 24 January 2010 (UTC)
 * Support per Ucuchua. Propaniac (talk) 15:32, 25 January 2010 (UTC)
 * The above discussion is preserved as an archive of a requested move. Please do not modify it. Subsequent comments should be made in a new section on this talk page. No further edits should be made to this section.

Anticoagulation is safe
10.1111/jth.13387 JFW &#124; T@lk  16:27, 28 September 2016 (UTC)

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Intent to Edit
Hello Wikipedia, Jocelyn.powell and I intend on editing this page. We will be adding and verifying sources as well as editing for clarity. If you are reading this, please feel free to suggest any edits. Thank you!

A xi (talk) 23:46, 31 July 2017 (UTC)
 * Thank you for picking up on this page. I've noticed that you are doing much more than sticking to adding and verifying sources. Could you outline which sections you will be expanding on and how? This outline can serve as a checklist of sorts for you and future editors. Mgiulietti (talk) 16:23, 7 August 2017 (UTC)

That's a great idea, thank you Mgiulietti! To clarify what our editing vision is, here it is: A xi (talk) 04:36, 13 August 2017 (UTC)
 * Introduction: Edit wording and distinguish brain tumor vs. brain metastasis.
 * Symptoms: Remove the laundry list of symptoms which included nausea and vomiting (extremely common symptoms). I pinpointed a few common symptoms specifically related to brain metastases, and explained them beyond simply listing them.
 * Diagnosis: Add this section for clarity. Previously the article just briefly mentioned diagnosis of brain metastasis but did not address how it is diagnosed.
 * Treatment: Add sources for statements made by the previous authors regarding treatment options. Expanded the chemotherapy section by updating the information (previously said there were no FDA approved treatments).


 * Thank you for strengthening this page. As part of the peer-review stage I would like to propose some suggestions for your consideration:
 * 1. Lead paragraph, fifth sentence beginning with "Lung cancer and melanoma...": I think this needs a citation.
 * Cited and moved. jocelyn.powell (talk) 4:32, 13 August 2017 (UTC)
 * 2. Lead paragraph, sixth sentence beginning with "As primary cancer...": I propose removing this sentence.  Its subject is primary cancer and treatment, NOT brain cancer or metastasis  It is also redundant since the same thing is essentially repeated in the last sentence ("modern treatments...").
 * I agree with this edit and removed the sentence as suggested. A xi (talk) 05:13, 13 August 2017 (UTC)
 * 3. Symptoms, third sentence beginning with "Often,..."): I think this needs a citation.
 * I removed this sentence seeing that it was from a previous author and seemed too vague.
 * 4. Symptoms, Paresthesia bullet: needs citation
 * Good catch. Added. A xi (talk) 05:35, 13 August 2017 (UTC)
 * 5. Symptoms, Increased intracranial pressure bullet: this is a sign rather than a symptom. Perhaps consider changing to the symptoms mentioned within this bullet, or changing the header.
 * Changed the way symptoms are presented. A xi (talk) 05:35, 13 August 2017 (UTC)
 * 6. Symptoms, Seizures bullet: this may not be clear to a general audience. Might consider: "Seizures: often indicate metastasis to the cerebellum."  The link to supratentorial region states that region is otherwise known as the cerebellum.
 * Could you please clarify this suggestion. The supratentorial region is the region above the cerebellum and is referring to the cerebral cortex which is often involved when seizures are present. jocelyn.powell ([[User

talk:Jocelyn.powell|talk]]) 10:49, 13 August 2017 (UTC)
 * Yes, sorry for the confusion. I meant to say "cerebral cortex" rather than cerebellum in my initial comment.  My suggestion is to use this instead of "supratentorial" region; either work but I think "cerebral cortex" may be more easily understood by a general audience.
 * Ah I see! This is done. jocelyn.powell (talk) 02:50, 13 August 2017 (UTC)
 * 7. Symptoms, Ataxia bullet: I suggest removing "the most likely site of metastasis within the brain is the cerebral cortex, however," from this bullet. It doesn't seem to be the right place for this bit of information, and if you make the above change to bullet Seizures that will address the cerebellum.  My suggestion would be to find a different location with this information.
 * Changed. jocelyn.powell (talk) 02:50, 13 August 2017 (UTC)
 * 8. Causes: I think this section is a more appropriate location for the fifth sentence of the Lead ("Lung cancer and melanoma..."). It will make the lead more concise; consider using it after the the Cause bullets.
 * Changed. jocelyn.powell (talk) 02:50, 13 August 2017 (UTC)
 * 9. Treatment, Symptomatic care, Corticosteroids: The third and fourth sentences ("Although..." and "In addition...") need citations.
 * Citations added. jocelyn.powell (talk) 04:47, 13 August 2017 (UTC)
 * 10. Treatment, Symptomatic care, Anticonvulsants: first sentence needs citation.
 * Added. jocelyn.powell (talk) 05:09, 13 August 2017 (UTC)
 * 11. Treatment, Symptomatic care, Anticonvulsants: the second sentence ("This is...") is particularly confusing.  What other patients? I thought we were already discussing seizure patients.  Also the structure and punctuation needs to be addressed. Consider re-writing the sentence.
 * Removed. jocelyn.powell (talk) 05:09, 13 August 2017 (UTC)
 * 11. Treatment, Symptomatic care, Anticonvulsants: The third sentence ("Phenytoin...") can be condensed for fluidity. Consider: "Phenytoin is the most prescribed drug for severe seizures; a common side effect of Phenytoin reported by patients with brain metastases is rash."
 * Updated. jocelyn.powell (talk) 05:09, 13 August 2017 (UTC)
 * 12. Treatment, Symptomatic care, Anticonvulsants: last sentence ("Valproic acid...") needs citation.
 * Updated. jocelyn.powell (talk) 05:09, 13 August 2017 (UTC)
 * 13. Treatment, Radiotherapy: Please clarify; the first sentence mentions this treatment is "critical" yet the second sentence states it "does appear at least somewhat effective." Can you strengthen this by saying how it is effective? (does this treatment shrink the tumor(s), or...?). It may also need a citation.
 * Updated. jocelyn.powell (talk) 05:31, 13 August 2017 (UTC)
 * 14. Treatment, Radiotherapy: The third sentence needs citation.
 * Updated. jocelyn.powell (talk) 05:31, 13 August 2017 (UTC)
 * 15. Treatment, Surgery: Consider splitting the first sentence into two for clarity. Consider: "Brain metastases are often managed surgically with maximum surgical resection followed by stereotactic radiosurgery or whole-brain irradiation. This delivers superior survival rates compared to whole brain irradiation alone. (This second part/sentence needs a citation.)
 * Updated. jocelyn.powell (talk) 05:09, 13 August 2017 (UTC)
 * 16. Treatment, Surgery: Consider restructuring for clarity. Particularly confusing is "patients with one metastatic brain lesion, limited, absent, or controlled systemic disease" (structure?) and "good performance status" (what is this?).
 * Done. jocelyn.powell (talk) 04:16, 13 August 2017 (UTC)
 * 17. Treatment, Stereostatic radiosurgery: consider removing this paragraph entirely. It seems redundant to what was already discussed about this treatment and its effects in the Surgery paragraph.
 * I agree with this edit. The paragraph has been removed. A xi (talk) 05:10, 13 August 2017 (UTC)
 * 18. Treatment, Chemotherapy: Consider removing the second sentence ("However..."). It seems to be a tangent discussing cancer other than the article's topic; it was already mentioned that this treatment is not primary for the article topic of brain metastases, so why go into what this irrelevant treatment can be used for?
 * What this is going at is that chemotherapy is not frequently used, but we don't want to completely disregard the use because it is indicated in some instances, thus is not completely "irrelevant." Remember that metastases come from a primary tumor. A xi (talk) 05:10, 13 August 2017 (UTC)
 * 19. Treatment, Chemotherapy: third sentence ("An experimental...") needs citation.
 * Added. jocelyn.powell (talk) 03:50, 13 August 2017 (UTC)
 * 20. Treatment, Chemotherapy: Consider removing the last sentence ("In 2015,...) or state specifically how it can be used for brain metastases. The sentence appears to be about a drug that can be used for a cancer other than the article's topic. The mention of Xalkori seems belated and (if kept in this paragraph) should be mentioned before "whose condition worsened after use or were unable to take another medication" for clarification.
 * Noted. I figured that I should not let the reader immediately draw conclusions, so I added a sentence here that should clear things up. A xi (talk) 05:10, 13 August 2017 (UTC)
 * 21. Prognosis: Third sentence needs citation. Also, is there a statistic for a mean/average available?
 * Added. jocelyn.powell (talk) 03:24, 13 August 2017 (UTC)

I apologize if the above suggestions seem like a lot but it really is just detail work and I wanted to be clear with my proposals. The article's tone stays neutral and the headers reflect the manual of style. I will later make another pass through the article to check links and sources. I will post again when I have done this. Thank you again for improving this article. It is a very important topic. hbc2020 23:43, 12 August 2017 (UTC) — Preceding unsigned comment added by Holly.calderon (talk • contribs)


 * I reviewed the sources. I could not access #3 or #11, but instead received an error/resource cannot be found.

Moving to B class status
Thank you for providing updates to this article. I'd like to see it moved to B status, but I do not believe it is quite there. Mgiulietti (talk) 15:27, 23 August 2017 (UTC)
 * Move palliative care wording at the start of treatment to a new section called "management." Palliative care isn't really "treatment" as it does not treat. Such a management section could then be expanded.
 * An Epidemiology section with some stats on prevalence. Include stats from outside the united states too if possible.
 * A history section that discusses how this condition was previous diagnosed, treated, etc.
 * B articles typically have extra smaller sections of related but tangential information at the end like famous cases (like notable people) who have had this condition.
 * B articles typically have an expanded section under the main image on the right. See this article under the photo of the eye to see what I mean.
 * Please see the page on article classification once this is done and if it meets the standards it may be moved to B status.

epidemiology
Hi, I added an epidemiology section to this article, and referenced many studies throughout. Could someone make sure it is up to standards? Thank you. — Preceding unsigned comment added by Albertdondy (talk • contribs) 16:56, 1 April 2019 (UTC)