1943 Rochester Yellowjackets football team

The 1943 Rochester Yellowjackets football team was an American football team that represented the University of Rochester as an independent during the 1943 college football season. In their fourth and final year under head coach Dudley DeGroot, the Yellowjackets compiled a 6–1 record and were ranked at No. 75 among the nation's college and military service teams in the final 1943 Litkenhous Ratings. Rochester defeated Yale, which was ranked No. 86 by Litkenhous, and split a pair of games with Colgate, which was ranked No. 60.

The 1943 Rochester team was composed largely of Marine Corps and Navy trainees who were transferred to the school as part of the V-12 Navy College Training Program. The incoming transfers included quarterback Eddie Fox (from Syracuse), center Ray Whelan (from LSU), and tackle Steve Skapinec (from New Mexico).

The team played its home games at River Campus Stadium in Rochester, New York.