1980 NCAA Division I baseball tournament

The 1980 NCAA Division I baseball tournament was played at the end of the 1980 NCAA Division I baseball season to determine the national champion of college baseball. The tournament concluded with eight teams competing in the College World Series, a double-elimination tournament in its thirty fourth year. Eight regional competitions were held to determine the participants in the final event. Seven regions held a four team, double-elimination tournament while one region included six teams, resulting in 34 teams participating in the tournament at the conclusion of their regular season, and in some cases, after a conference tournament. The thirty-fourth tournament's champion was Arizona, coached by Jerry Kindall. The Most Outstanding Player was Terry Francona of the Arizona.

Regionals
Seven of the eight regionals were played as 4-team double-elimination tournaments. One regional was played as a 6-team double-elimination tournament. The winner of each regional moved onto the College World Series.

Northeast Regional
Games played in Orono, Maine.

West Regional
Games played in Tucson, Arizona.

South Regional
Games played in Tallahassee, Florida.

Central Regional
Games played in Austin, Texas.

Atlantic Regional
Games played in Clemson, South Carolina.

East Regional
Games played in Miami, Florida.

Mideast Regional
Games played in Ann Arbor, Michigan.

Midwest Regional
Games played in Tulsa, Oklahoma.

All-Tournament Team
The following players were members of the All-Tournament Team.

Notable players

 * Arizona: Greg Bargar, Casey Candaele, Terry Francona, Craig Lefferts, John Moses, Dwight Taylor, Ed Vosberg, Kevin Ward
 * California: Chuck Cary, Rod Booker, Chuck Hensley, Bob Melvin
 * Clemson: Mike Brown, Jimmy Key, Danny Sheaffer, Tim Teufel
 * Florida State: Mike Fuentes, Jim Weaver
 * Hawaii: Chuck Crim
 * Miami (FL): Neal Heaton, Ross Jones, Mike Pagliarulo
 * Michigan: Steve Ontiveros, Jim Paciorek
 * St. John's: John Franco, Frank Viola