1991 Virginia Slims of Houston – Singles

Katerina Maleeva was the defending champion, but lost in the second round to Christína Papadáki.

Monica Seles won the title by defeating Mary Joe Fernández 6–4, 6–3 in the final.

Seeds
The first four seeds received a bye into the second round. • # Monica Seles (champion)

• # 🇺🇸 Mary Joe Fernández (final)

• # 🇺🇸 Zina Garrison (second round)

• # 🇧🇬 Katerina Maleeva (quarterfinals)

• # Leila Meskhi (withdrew)

• # 🇮🇹 Sandra Cecchini (semifinals)

• # 🇺🇸 Susan Sloane (first round)

• # 🇦🇷 Mercedes Paz (first round)

• # 🇺🇸 Gretchen Magers (first round)