2000 Northwestern State Demons football team

The 2000 Northwestern State Demons football team represented Northwestern State University as a member of the Southland Conference during the 2000 NCAA Division I-AA football season. Led by first-year head coach Steve Roberts, the Demons compiled an overall record of 6–5 with a mark of 3–4 in conference play, tying in fifth place in the Southland. Northwestern State played home games at Harry Turpin Stadium in Natchitoches, Louisiana.

In the spring of 2001, Northwestern State forfeited two wins from the 2000 season, over Troy State and Nicholls State, because an ineligible player had participated for the Demons in those games. With the forfeit, the Demons' record dropped to 4–7 overall and 1–6 in conference play, tying in last place in the Southland.