2006 Northwestern State Demons football team

The 2006 Northwestern State Demons football team represented Northwestern State University as a member of the Southland Conference during the 2006 NCAA Division I FCS football season. Led by fifth-year head coach Scott Stoker, the Demons compiled an overall record of 4–7 with a mark of 2–4 in conference play, tying for fifth place in the Southland. Northwestern State played home games at Harry Turpin Stadium in Natchitoches, Louisiana.