2003 Abierto Mexicano Telefonica Movistar – Women's singles

Katarina Srebotnik was the defending champion, but lost in second round to Petra Mandula.

Amanda Coetzer won the title by defeating Mariana Díaz Oliva 7–5, 6–3 in the final. It was the 9th and last title for Coetzer in her career.

Seeds
The first two seeds received a bye into the second round. • # 🇷🇺 Elena Dementieva (second round)

• # Amanda Coetzer (champion)

• # 🇦🇷 Paola Suárez (first round, retired due to a back injury)

• # Katarina Srebotnik (second round)

• # 🇪🇸 Magüi Serna (first round)

• # Tina Pisnik (first round)

• # 🇫🇷 Émilie Loit (semifinals)

• # Emmanuelle Gagliardi (second round)