2010–11 in Uruguayan football

Primera División
Source: RSSSF
 * Apertura champion: Defensor Sporting (4th title)
 * Top scorer: Santiago García (15 goals)
 * Clausura champion: Nacional (6th title)
 * Top scorer: Cristian Palacios (15 goals)
 * Overall champion: Nacional (43rd title)
 * Top scorer: Santiago García (23 goals)
 * International qualifiers:
 * Copa Libertadores:
 * Group Stage: Nacional and Defensor Sporting
 * Preliminary Round: Peñarol
 * Copa Sudamericana:
 * Second Stage: Nacional
 * First Stage: Fénix and Bella Vista
 * Relegated: Central Español, Tacuarembó and Miramar Misiones

Second Division

 * Segunda División champion: Rentistas (4th title)
 * Segunda División runners-up: Cerrito
 * Top scorers: Santiago Bello and Joel Burgueño (13 goals)

Promoted teams
Source: RSSSF
 * Rentistas
 * Cerrito
 * Cerro Largo

Defensor Sporting

 * 2010 Copa Sudamericana

'' Defensor Sporting eliminated on goal difference 3–4. ''

Liverpool

 * 2011 Copa Libertadores

'' Liverpool eliminated on points 1–4. ''

Nacional

 * 2011 Copa Libertadores

Nacional eliminated by finishing in 3rd place in their group.

Peñarol

 * 2010 Copa Sudamericana

'' Peñarol eliminated on away goals. ''


 * 2011 Copa Libertadores

'' Peñarol defeated by Santos on points 1–4. ''

River Plate

 * 2010 Copa Sudamericana

'' River Plate eliminated on away goals. ''

Senior team
This section covers Uruguay's senior team matches from the end of the 2010 FIFA World Cup until the end of the 2011 Copa América.