3-Allylfentanyl

3-Allylfentanyl is an opioid analgesic that is an analogue of fentanyl.

3-Allylfentanyl has effects similar to fentanyl, although it is only 0.13x-0.14x as potent by weight.

The decreased potency of this analogue caused by the addition of the allyl group makes it somewhat less dangerous than fentanyl itself (ED50(rat) of 80μg/kg vs 11μg/kg for fentanyl), although this is relative. For comparison, carfentanil is at least 20-30x as potent as fentanyl.

Side Effects
Side effects of fentanyl analogs vary based on strength and are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening.