Brazilian Controlled Drugs and Substances Act

The Brazilian Controlled Drugs and Substances Act (Regulamento Técnico sobre substâncias e medicamentos sujeitos a controle especial), officially Portaria nº 344/1998, is Brazil's federal drug control statute, issued by the Ministry of Health through its National Health Surveillance Agency (Anvisa). The act also serves as the implementing legislation for the Single Convention on Narcotic Drugs, the Convention on Psychotropic Substances, and the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances in the country.

The list was last updated in September 2023.

Terminology:


 * Prescription notification - a standardized document intended for notifying Anvisa of the prescription of medications. Written by the doctor and retained by the drugstore
 * Prescription - a written medication order that provides usage instructions for the patient.
 * Special control prescription - a prescrition that is filled out in two copies, one that is retained by the drugstore, and another stays with the patient for usage guidance. It can be provided in a digital signed form.

Class A3

 * Amphetamine
 * Cathine
 * Chlorphentermine
 * Dexamphetamine
 * Dronabinol - Synthetic form with no other cannabinoid.
 * Phenmetrazine
 * Phencyclidine
 * Phenethylline
 * Levamphetamine
 * Levomethamphetamine
 * Lisdexamfetamine
 * Methylphenidate
 * Methylsynephrine
 * Thamphetamine
 * Cannabis sativa derivates containing up to 30mg/mL THC and 30mg/mL CBD

Class A1

 * Acetylmethadol
 * Alphacetylmethadol
 * Alphameprodine
 * Alphamethadol
 * Alphaprodine
 * Alfentanil
 * Allylprodine
 * Anileridine
 * Bezitramide
 * Benzethidine
 * Benzylmorphine
 * Benzoylmorphine
 * Betaacetylmethadol
 * Betameprodine
 * Betamethadol
 * Betaprodine
 * Buprenorphine
 * Butorphanol
 * Clonitazene
 * Codoxime
 * Concentrated opium poppy straw
 * Dextromoramide
 * Diampromide
 * Diethylthiambutene
 * Diphenoxylate
 * Difenoxin
 * Dihydromorphine
 * Dimepheptanol
 * Dimenoxadol
 * Dimethylthiambutene
 * Dioxaphetyl butyrate
 * Dipipanone
 * Drotebanol
 * Ethylmethylthiambutene
 * Etonitazene
 * Etoxeridine
 * Phenadoxone
 * Phenampromide
 * Phenazocine
 * Phenomorphan
 * Phenoperidine
 * Fentanyl
 * Furethidine
 * Hydrocodone
 * Hydromorphinol
 * Hydromorphone
 * Hydroxypethidine
 * Methadone intermediate
 * Moramide intermediate
 * Pethidine intermediate A
 * Norpethidine (Pethidine intermediate B)
 * Pethidinic acid (Pethidine intermediate C)
 * Isomethadone
 * Levophenacylmorphan
 * Levomethorphan
 * Levomoramide
 * Levorphanol
 * Methadone
 * Metazocine
 * Methyldesorphine
 * Methyldihydromorphine
 * Metopon
 * Myrophine
 * Morpheridine
 * Morphine
 * Morinamide
 * Nicomorphine
 * Noracymethadol
 * Norlevorphanol
 * Normethadone
 * Normorphine
 * Norpipanone
 * Codeine-N-oxide
 * Morphine-N-oxide
 * Opium
 * Oripavine
 * Oxycodone
 * Oxymorphone
 * Pethidine
 * Piminodine
 * Piritramide
 * Proheptazine
 * Properidine
 * Racemethorphan
 * Racemoramide
 * Racemorphan
 * Remifentanil
 * Sufentanil
 * Tapentadol
 * Thebacon
 * Thebaine
 * Tilidine
 * Trimeperidine

Class A2

 * Acetyldihydrocodeine
 * Codeine
 * Dextropropoxyphene
 * Dihydrocodeine
 * Ethylmorphine (Dionine)
 * Pholcodine
 * Nalbufina
 * Nalorphine
 * Nicocodine
 * Nicodicodine
 * Norcodeine
 * Propiram
 * Tramadol

Class A3

 * Amphetamine
 * Cathine
 * Chlorphentermine
 * Dexamphetamine
 * Dronabinol - Synthetic form with no other cannabinoid.
 * Phenmetrazine
 * Phencyclidine
 * Phenethylline
 * Levamphetamine
 * Levomethamphetamine
 * Lisdexamfetamine
 * Methylphenidate
 * Methylsynephrine
 * Thamphetamine
 * Cannabis sativa derivates containing up to 30mg/mL THC and 30mg/mL CBD

Class B1

 * Allobarbital
 * Alprazolam
 * Amineptine
 * Amobarbital
 * Aprobarbital
 * Armodafinil
 * Barbexaclone
 * Barbital
 * Bromazepam
 * Bromazolam
 * Brotizolam
 * Butabarbital
 * Butalbital
 * Camazepam
 * Ketamine
 * Ketazolam
 * Cyclobarbital
 * Clobazam
 * Clonazepam
 * Clonazolam
 * Chlorazepam (CAS:, , )
 * Clorazepate
 * Chlordiazepoxide
 * Ethyl chloride
 * Methylene chloride/dichloromethane
 * Clotiazepam
 * Cloxazolam
 * Delorazepam
 * Diazepam
 * Diclazepam
 * Esketamine
 * Estazolam
 * Eszopiclone
 * Ethchlorvynol
 * Ethylamphetamine (N-Ethylamphetamine)
 * Ethinamate
 * Etizolam
 * Phenazepam
 * Phenobarbital
 * Flualprazolam
 * Flubromazolam
 * Fludiazepam
 * Flunitrazepam
 * Flurazepam
 * GBL
 * GHB
 * Glutethimide
 * Halazepam
 * Haloxazolam
 * Lefetamine
 * Ethyl loflazepate
 * Loprazolam
 * Lorazepam
 * Lormetazepam
 * Medazepam
 * Meprobamate
 * Mesocarb
 * Methylphenobarbital (prominal)
 * Methyprylon
 * Midazolam
 * Modafinil
 * Nimetazepam
 * Nitrazepam
 * Fencamfamin
 * Nordazepam
 * Oxazepam
 * Oxazolam
 * Pemoline
 * Pentazocine
 * Pentobarbital
 * Perampanel
 * Pinazepam
 * Pipradrol
 * Pyrovalerone
 * Prazepam
 * Prolintane
 * Propylhexedrine
 * Secbutabarbital
 * Secobarbital
 * Temazepam
 * Tetrazepam
 * Thiamylal
 * Thiopental
 * Triazolam
 * Trichlorethylene
 * Trihexyphenidyl
 * Vinylbital
 * Zaleplon
 * Zolpidem
 * Zopiclone
 * Cannabis derivates containing up to 0,2% THC

Class B2

 * Aminorex
 * Amfepramone
 * Fenproporex
 * Phendimetrazine
 * Phentermine
 * Mazindol
 * Mefenorex
 * Sibutramine

Class C1

 * Acepromazine
 * Valproic acid
 * Agomelatine
 * Amantadine
 * Amisulpride
 * Amitriptyline
 * Amoxapine
 * Aripiprazole
 * Asenapine
 * Atomoxetine
 * Azacyclonol
 * Beclamide
 * Benactyzine
 * Benfluorex
 * Benzydamine
 * Benzoctamine
 * Benzquinamide
 * Biperiden
 * Brexpiprazole
 * Brivaracetam
 * Bupropion
 * Buspirone
 * Butaperazine
 * Butriptyline
 * Cannabidiol - Synthetic form with no other cannabinoid.
 * Captodiame
 * Carbamazepine
 * Caroxazone
 * Celecoxib
 * Cyclarbamate
 * Cyclexedrine (CAS:, )
 * Cyclopentolate
 * Cisapride
 * Citalopram
 * Clomacran
 * Clomethiazole
 * Clomipramine
 * Chloralodol
 * Chlorpromazine
 * Chlorprothixene
 * Clotiapine
 * Clozapine
 * Dapoxetine
 * Desflurane
 * Desipramine
 * Desvenlafaxine
 * Deutetrabenazine
 * Dexetimide
 * Dexmedetomidine
 * Dibenzepine
 * Dimetacrine
 * Disopyramide
 * Disulfiram
 * Divalproex sodium
 * Dixyrazine
 * Donepezil
 * Doxepin
 * Droperidol
 * Duloxetine
 * Ectylurea (See Acylurea) (CAS:, )
 * Emylcamate
 * Enflurane
 * Entacapone
 * Escitalopram
 * Etomidate
 * Etoricoxib
 * Ethosuximide
 * Levophacetoperane
 * Phenprobamate
 * Phenaglycodol
 * Phenelzine
 * Pheniprazine
 * Phenytoin
 * Fluphenazine
 * Flumazenil
 * Fluoxetine
 * Flupentixol
 * Fluvoxamine
 * Gabapentin
 * Galantamine
 * Haloperidol
 * Halothane
 * Chloral hydrate
 * Etodroxizine (Hydrochlorbenzethylamine)
 * Hydroxydione
 * Homofenazine
 * Imiclopazine
 * Imipramine
 * Imipraminoxide
 * Iproclozide
 * Isocarboxazid
 * Isoflurane
 * Cenestil (Isopropyl-crotonyl-urea) (CAS:, )
 * Lacosamide
 * Lamotrigine
 * Leflunomide
 * Levetiracetam
 * Levomepromazine
 * Levomilnacipran
 * Lisuride
 * Lithium
 * Loperamide
 * Loxapine
 * Lumiracoxib
 * Lurasidone
 * Mavacamten
 * Maprotiline
 * Meclofenoxate
 * Mephenoxalone
 * Mefexamide
 * Memantine
 * Mepazine
 * Mesoridazine
 * Methylnaltrexone
 * Methylpentynol
 * Methysergide
 * Metixene
 * Methopromazine (CAS:, )
 * Methoxyflurane
 * Mianserin
 * Milnacipran
 * Miltefosine
 * Minaprine
 * Mirtazapine
 * Misoprostol - Hospital authorization only.
 * Moclobemide
 * Molnupiravir
 * Moperone
 * Naloxone
 * Naltrexone
 * Nefazodone
 * Nialamide
 * Isobutyl nitrite
 * Nomifensine
 * Nortriptyline
 * Noxiptiline
 * Olanzapine
 * Opipramol
 * Oxcarbazepine
 * Oxybuprocaine
 * Hydroxyphenamate
 * Oxypertine
 * Paliperidone
 * Parecoxib
 * Paroxetine
 * Penfluridol
 * Perphenazine
 * Pergolide
 * Pericyazine
 * Pimozide
 * Pipamperone
 * Pipotiazine
 * Pramipexole
 * Pregabalin
 * Primidone
 * Prochlorperazine
 * Promazine
 * Propanidid
 * Propiomazine
 * Propofol
 * Prothipendyl
 * Protriptyline
 * Proparacaine
 * Quetiapine
 * Ramelteon
 * Rasagiline
 * Reboxetine
 * Ribavirin
 * Rimonabant
 * Risperidone
 * Rivastigmine
 * Rofecoxib
 * Ropinirole
 * Rotigotine
 * Rufinamide
 * Selegiline
 * Sertraline
 * Sevoflurane
 * Sulpiride
 * Sultopride
 * Tacrine
 * Teriflunomide
 * Tetrabenazine
 * Tetracaine
 * Tiagabine
 * Tianeptine
 * Tiapride
 * Thioproperazine
 * Thioridazine
 * Thiothixene
 * Tolcapone
 * Topiramate
 * Tranylcypromine
 * Trazodone
 * Triclofos
 * Trifluoperazine
 * Trifluperidol
 * Trimipramine
 * Troglitazone
 * Valdecoxib
 * Sodium valproate
 * Venlafaxine
 * Veralipride
 * Vigabatrin
 * Vilazodone
 * Vortioxetine
 * Ziprasidone
 * Zotepine
 * Zuclopenthixol

Class C2

 * Acitretin
 * Adapalene
 * Bexarotene
 * Isotretinoin
 * Tretinoin

Class C3

 * Thalidomide
 * Lenalidomide
 * Pomalidomide

Class C4
List revoked in September 2016.


 * Abacavir
 * Amprenavir
 * Atazanavir
 * Darunavir
 * Delavirdine
 * Didanosine (ddI)
 * Dolutegravir
 * Efavirenz
 * Enfuvirtide
 * Stavudine (d4T)
 * Etravirine
 * Fosamprenavir
 * Indinavir
 * Lamivudine (3TC)
 * Lopinavir
 * Maraviroc
 * Nelfinavir
 * Nevirapine
 * Raltegravir
 * Ritonavir
 * Saquinavir
 * Tenofovir
 * Tipranavir
 * Zalcitabine (ddC)
 * Zidovudine (AZT)

Class C5

 * Androstanolone
 * Bolasterone
 * Boldenone
 * Chlorodehydromethyltestosterone
 * Clostebol
 * Dehydrochlormethyltestosterone
 * Drostanolone
 * Stanolone
 * Stanozolol
 * Ethylestrenol
 * Fluoxymesterone
 * Formebolone
 * Gestrinone
 * Mesterolone
 * Methandienone
 * Methandranone
 * Methandriol
 * Methenolone
 * Methyltestosterone
 * Mibolerone
 * Nandrolone
 * Norethandrolone
 * Oxandrolone
 * Oxymesterone
 * Oxymetholone
 * Prasterone (dehydroepiandrosterone - DHEA)
 * Somapacitan
 * Somatrogon
 * Somatropin (Human Growth Hormone)
 * Testosterone
 * Trenbolone

Class D1

 * 1-Boc-4-AP (CAS:, )
 * 1-phenyl-2-propanone
 * 3,4-MDP-2-P methyl glycidic acid (PMK glycidic acid)
 * 3,4-MDP-2-P methyl glycidate (PMK glycidate)
 * 3,4-Methylenedioxyphenyl-2-propanone
 * 4-AP (N-Phenyl-4-piperidinamine)
 * Anthranilic acid
 * Phenylacetic acid
 * Lysergic acid
 * N-Acetylanthranilic acid
 * Alpha-phenylacetoacetonitrile (APAAN) (CAS:, )
 * Alpha-phenylacetoacetamide (APAA) (CAS:, )
 * 4-ANPP
 * Dihydroergometrine
 * Dihydroergotamine
 * Ephedrine
 * Ergometrine
 * Ergotamine
 * Etafedrine
 * Helional
 * Isosafrole
 * Methyl alpha-acetylphenylacetate (MAPA) - (CAS:, )
 * Norfentanyl
 * Sassafras oil
 * Long pepper oil
 * Piperidine
 * Piperonal
 * Pseudoephedrine
 * N-phenethyl-4-piperidinone (NPP)
 * Safrole

Class D2

 * Acetone
 * Hydrochloric acid
 * Sulfuric acid
 * Acetic anhydride
 * Ethyl chloride
 * Methylene Chloride
 * Chloroform
 * Ethyl Ether
 * Methyl ethyl ketone
 * Potassium permanganate
 * Sodium sulphate
 * Toluene
 * Trichlorethylene

Class E

 * Cannabis sativa - except for registed products under allowed dosage mentioned in Class A3.
 * Claviceps paspali (Ergot)
 * Datura suaveolens
 * Erythroxylum coca
 * Lophophora williamsii (Coto Peyote)
 * Mitragyna speciosa
 * Papaver somniferum
 * Prestonia amazonica
 * Salvia divinorum

Class F1

 * 2-Methyl-AP-237 (methyl analogue of bucinnazine)
 * 3-Methylfentanyl
 * 3-Methylthiofentanyl
 * 4-Fluoroisobutyrfentanyl
 * 7-Hydroxymitragynine
 * Acetyl-alpha-methylfentanyl
 * Acetylfentanyl
 * Acetorphine
 * Acryloylfentanyl
 * AH-7921
 * Alpha-methylfentanyl
 * Alpha-methylthiofentanyl
 * Beta-hydroxy-3-methylfentanyl
 * Beta-hydroxyfentanyl
 * Brorphine
 * Butyrfentanyl
 * Butonitazene
 * Carfentanil
 * Ketobemidone
 * Cyclopropylfentanyl
 * Cocaine
 * Crotonylfentanyl
 * Desomorphine
 * Dihydroetorphine
 * Ecgonine
 * Etazene (Etodesnitazene)
 * Etonitazepyne
 * Etorphine
 * Furanylfentanyl
 * Heroin
 * Isotonitazene
 * MDPV
 * Metonitazene
 * Methoxyacetylfentanyl
 * Mitragynine
 * MPPP
 * MT-45
 * Ocfentanil
 * Orthofluorofentanyl
 * Parafluorobutyrfentanyl
 * Parafluorofentanyl
 * PEPAP
 * Protonitazene
 * Tetrahydrofuranylfentanyl
 * Thiofentanyl
 * U-47700
 * Valerylfentanyl

Class F2

 * LSD
 * 1B-LSD
 * 1cP-LSD
 * 1P-LSD
 * 2C-B
 * 2C-C
 * 2C-D
 * 2C-E
 * 2C-F
 * 2C-I
 * 2C-T-2
 * 2C-T-7
 * 2-MeO-Diphenidine
 * 3-Fluorophenmetrazine
 * 3-MeO-PCP
 * 3-MMC
 * 4-AcO-DMT
 * 4-Bromomethcathinone
 * 4-Chloro-alpha-PVP
 * 4-Chloromethcathinone (4-CMC)
 * 4-Fluoroamphetamine (4-FA)
 * 4-Fluoromethcathinone
 * 4F-MDMB-BINACA
 * 4-HO-MIPT
 * 4-MEAPP
 * 4-MEC
 * 4-Methylaminorex
 * 4-MTA
 * 4,4'-DMAR
 * 5-APB
 * 5-APDB
 * 5C-MDA-19 (BZO-POXIZID, CAS:, )
 * 5-EAPB
 * 5F-AB-FUPPYCA
 * 5F-ADB
 * 5F-AKB48
 * 5F-AMB-PINACA
 * 5F-MDA-19 (5F-BZO-POXIZID, )
 * 5F-MDMB-PICA
 * 5F-PB-22
 * 5-IAI
 * 5-MAPDB
 * 5-MeO-AMT
 * 5-MeO-DALT
 * 5-MeO-DIPT
 * 5-MeO-DMT
 * 5-MeO-MIPT
 * 25B-NBOH
 * 25B-NBOMe
 * 25C-NBF
 * 25C-NBOH
 * 25C-NBOMe
 * 25D-NBOMe
 * 25E-NBOH
 * 25E-NBOMe
 * 25H-NBOH
 * 25H-NBOMe
 * 25I-NBF
 * 25I-NBOH
 * 25I-NBOMe
 * 25N-NBOMe
 * 25P-NBOMe
 * 25T2-NBOMe
 * 25T4-NBOMe
 * 25T7-NBOMe
 * 30C-NBOMe
 * AB-CHMINACA
 * AB-FUBINACA
 * AB-PINACA
 * ADB-BUTINACA
 * ADB-CHMINACA
 * ADB-FUBIATA
 * ADB-FUBINACA
 * ALD-52
 * Alpha-D2Pv
 * Alpha-EAPP
 * Alpha-PHP
 * alpha-PiHP
 * Alpha-PVP
 * AKB48
 * AM-2201
 * AMT
 * Benzphetamine
 * Bk-DMBDB
 * Brolamphetamine
 * BZO-4en-POXIZID (4en-pentyl MDA-19)
 * BZO-CHMOXIZID
 * BZP
 * Cathinone
 * CH-PIATA
 * Clobenzorex
 * CUMYL-4CN-BINACA
 * CUMYL-PEGACLONE
 * DET
 * Diphenidine
 * Dihydro-LSD (ChemSpider ID: 67024742) (8β)-N,N-Diethyl-6-methyl-9,10-didehydro-2,3-dihydroergoline-8-carboxamide
 * Dimethylone
 * DMA
 * DMAA
 * DMBA
 * DMHP
 * DMT
 * DOC
 * DOET
 * DOI
 * EAM-2201
 * Ergine
 * Eticyclidine
 * Ethylphenidate
 * Ethylone
 * Etryptamine
 * Eutylone
 * FUB-AMB
 * Isopropylbenzylamine
 * JWH-018
 * JWH-071
 * JWH-072
 * JWH-073
 * JWH-081
 * JWH-098
 * JWH-122
 * JWH-210
 * JWH-250
 * JWH-251
 * JWH-252
 * JWH-253
 * MAM-2201
 * MAM-2201 N-(4-hydroxypentyl) (CAS:, , )
 * MAM-2201 N-(5-chloropentyl) (CAS:, , )
 * MDMB-4en-PINACA
 * MDMB-5Br-INACA
 * mCPP
 * MDA-19 (BZO-HEXOXIZID)
 * MDAI
 * MDE
 * MDMA
 * Mecloqualone
 * Mephedrone
 * Mescaline
 * Methallylescaline
 * Methanphetamine
 * Methaqualone
 * Methcathinone
 * Methylone
 * Methiopropamine
 * MMDA
 * MXE
 * N-acetyl-3,4-MDMC (CAS:, )
 * N-Ethylcathinone
 * N-Ethylhexedrone (hexen)
 * N-Ethylpentylone
 * Parahexyl
 * Pentedrone
 * Pentylone
 * PMA
 * PMMA
 * Psilocybin
 * Psilocin
 * RH-34
 * Rolicyclidine (PCPy)
 * Salvinorin A
 * DOM (STP)
 * Tenamfetamine
 * Tenocyclidine
 * THC - except for registed products under allowed dosage mentioned in Class A3.
 * TH-PVP
 * TMA
 * TFMPP
 * UR-144
 * XLR-11
 * Zipeprol

Class F3

 * Phenylpropanolamine (PPA) or norephedrine

Class F4

 * Dexfenfluramine
 * Dinitrophenol
 * Strychnine
 * Etretinate
 * Fenfluramine
 * Lindane
 * Terfenadine