Swimming at the 2022 Mediterranean Games – Women's 400 metre individual medley

The women's 400 metre individual medley competition at the 2022 Mediterranean Games was held on 1 July 2022 at the Aquatic Center of the Olympic Complex in Bir El Djir.

Records
Prior to this competition, the existing world and Mediterranean Games records were as follows:

Heats
The heats were started at 10:20.

Final
The final was held at 18:18.