Talk:XYYY syndrome

Category:Intersex variations
Where would I find the consensus about intersex not including duplicated "expected" sex chromosomes, as mentioned by @Vaticidalprophet? Not arguing, but curious. IAmNitpicking (talk) 18:30, 1 August 2022 (UTC)


 * These karyotypes are consistently excluded from descriptions of sex chromosome DSD/intersex (there is some dispute over ideal wording). Major best-practice/consensus descriptors of sex chromosome DSDs vary on whether they include Turner/Klinefelter or if they only include mosaic karyotypes with both Y and nullisomy-Y cells, but they do not include these; see here, here (the 'Chicago classification' which modern definitions are based on or heavily inspired by), here (paywall), some of the studies (probably most individually paywalled) in this major symposium (note particularly the large Egyptian sample of chromosomally intersex patients, of which none had any karyotypes like these despite their very high population prevalence)...
 * These are conditions where the sex-development phenotype is essentially indistinguishable from someone lacking the extra chromosome. Even by the definition of sex chromosome intersexuality that includes Klinefelter's et al, they're consistently excluded. Vaticidalprophet 03:15, 2 August 2022 (UTC)
 * Thank you. IAmNitpicking (talk) 17:53, 2 August 2022 (UTC)