2008 United States Senate election in Mississippi

The 2008 United States Senate election in Mississippi was held on November 4, 2008. The seat was regularly scheduled for election, unlike the special election taking place on the same day. Incumbent Republican U.S. Senator Thad Cochran won re-election to a sixth term.

Democratic

 * Erik R. Fleming, State Representative and nominee in 2006
 * Shawn O'Hara

Republican

 * Thad Cochran, incumbent U.S. Senator

Counties that flipped from Republican to Democratic

 * Tunica (Largest city: Tunica)
 * Coahoma (Largest city: Clarksdale)
 * Tallahatchie (Largest city: Charleston)
 * Quitman (Largest city: Lambert)
 * Sharkey (Largest city: Rolling Fork)
 * Issaquena (Largest city: Mayersville)
 * Clay (Largest city: West Point)
 * Marshall (Largest city: Holly Springs)
 * Noxubee (Largest city: Macon)
 * Kemper (Largest city: De Kalb)
 * Jasper (Largest city: Bay Springs)
 * Jefferson Davis (Largest city: Prentiss)
 * Adams (Largest city: Natchez)
 * Wilkinson (Largest city: Centreville)
 * Hinds (largest municipality: Jackson)
 * Jefferson (largest municipality: Fayette)
 * Claiborne (largest municipality: Port Gibson)
 * Washington (Largest city: Greenville)
 * Humphreys (Largest city: Belzoni)
 * Holmes (Largest city: Durant)
 * Bolivar (Largest city: Cleveland)
 * Sunflower (Largest city: Indianola)
 * LeFlore (Largest city: Greenwood)