List of United States senators from Mississippi

Mississippi was admitted to the Union on December 10, 1817, and elects senators to class 1 and class 2. Its current senators are Republicans Cindy Hyde-Smith and Roger Wicker. As of February 2022, 51 people have served as U.S. senators from Mississippi. John C. Stennis was Mississippi's longest-serving senator (1947–1989).

Mississippi last elected a Democrat in 1982, and both seats have been occupied by the Republicans since 1989.

List of senators
! rowspan=2 | 1 ! rowspan=11 | 1
 * - style="height:2em"
 * rowspan=2 align=left | Walter Leake.jpg Walter Leake
 * rowspan=2 | Democratic- Republican
 * rowspan=2 nowrap | Dec 10, 1817 – May 15, 1820
 * rowspan=2 | Elected in 1817.Resigned.
 * rowspan=4 | 1
 * rowspan=5 | 1
 * rowspan=5 | Elected in 1817.
 * rowspan=11 nowrap | Dec 10, 1817 – Mar 4, 1829
 * rowspan=6 | Democratic- Republican
 * rowspan=11 align=right | Thomas Hill Williams.jpg Thomas Hill Williams
 * rowspan=11 align=right | Thomas Hill Williams.jpg Thomas Hill Williams


 * - style="height:2em"


 * - style="height:2em"
 * colspan=3 | Vacant
 * nowrap | May 15, 1820 – Aug 30, 1820

! rowspan=4 | 2
 * - style="height:2em"
 * rowspan=4 align=left | DavidHolmesMS.jpg David Holmes
 * rowspan=3 | Democratic- Republican
 * rowspan=4 nowrap | Aug 30, 1820 – Sep 25, 1825
 * Elected to finish Leake's term.


 * - style="height:2em"
 * rowspan=3 | Re-election year unknown.Resigned to become Governor of Mississippi.
 * rowspan=6 | 2


 * - style="height:2em"
 * rowspan=6 | 2
 * rowspan=6 | Re-elected in 1823.
 * rowspan=6 | Re-elected in 1823.


 * - style="height:2em"
 * | Jacksonian
 * rowspan=5 | Jacksonian
 * rowspan=5 | Jacksonian


 * - style="height:2em"
 * colspan=3 | Vacant
 * nowrap | Sep 25, 1825 – Sep 28, 1825

! 3
 * - style="height:2em"
 * align=left | Powhatan Ellis.jpg Powhatan Ellis
 * | Jacksonian
 * nowrap | Sep 28, 1825 – Jan 28, 1826
 * Appointed to continue Holmes's term.Lost election to finish Holmes's term.

! 4
 * - style="height:2em"
 * align=left | Thomas Buck Reed.jpg Thomas Buck Reed
 * | Jacksonian
 * nowrap | Jan 28, 1826 – Mar 4, 1827
 * Elected to finish Holmes's term.Lost election to full term.

! rowspan=7 | 5
 * - style="height:2em"
 * rowspan=7 align=left | Powhatan Ellis.jpg Powhatan Ellis
 * rowspan=7 | Jacksonian
 * rowspan=7 nowrap | Mar 4, 1827 – Jul 16, 1832
 * rowspan=7 | Election year unknown.Resigned to become a U.S. District Judge.
 * rowspan=9 | 3

! 2
 * - style="height:2em"
 * rowspan=10 | 3
 * Elected in 1828.Died.
 * nowrap | Mar 4, 1829 – Nov 26, 1829
 * | Jacksonian
 * align=right | Thomas Buck Reed.jpg Thomas Buck Reed
 * align=right | Thomas Buck Reed.jpg Thomas Buck Reed


 * - style="height:2em"
 * nowrap | Nov 26, 1829 – Jan 6, 1830
 * colspan=3 | Vacant
 * colspan=3 | Vacant

! 3
 * - style="height:2em"
 * Elected to finish Reed's term.Died.
 * nowrap | Jan 6, 1830 – Jul 2, 1830
 * | Jacksonian
 * align=right | Robert H. Adams


 * - style="height:2em"
 * nowrap | Jul 2, 1830 – Oct 15, 1830
 * colspan=3 | Vacant
 * colspan=3 | Vacant

! rowspan=6 | 4
 * - style="height:2em"
 * rowspan=6 | Appointed to continue Adams's term.Elected in 1830 to finish Adams's term.Lost re-election.
 * rowspan=6 nowrap | Oct 15, 1830 – Mar 4, 1835
 * | Jacksonian
 * rowspan=6 align=right | GeorgePoindexter.jpg George Poindexter


 * - style="height:2em"
 * rowspan=5 | National Republican
 * rowspan=5 | National Republican


 * - style="height:2em"
 * colspan=3 | Vacant
 * nowrap | Jul 16, 1832 – Nov 12, 1832

! rowspan=5 | 6
 * - style="height:2em"
 * align=left | SenatorJohnBlack.jpg John Black
 * | Jacksonian
 * nowrap | Nov 12, 1832 – Mar 4, 1833
 * Appointed to finish Ellis's term.


 * - style="height:2em"
 * colspan=2 | Vacant
 * nowrap | Mar 4, 1833 – Nov 22, 1833
 * Legislature failed to elect.
 * rowspan=7 | 4


 * - style="height:2em"
 * rowspan=3 align=left | SenatorJohnBlack.jpg John Black
 * rowspan=2 | National Republican
 * rowspan=3 nowrap | Nov 22, 1833 – Jan 22, 1838
 * rowspan=3 | Elected late.Resigned.

! rowspan=9 | 5
 * - style="height:2em"
 * rowspan=6 | 4
 * rowspan=6 | Elected in 1835.
 * rowspan=9 nowrap | Mar 4, 1835 – Mar 5, 1845
 * | Jacksonian
 * rowspan=9 align=right | Robert J Walker.jpg Robert J. Walker
 * rowspan=9 align=right | Robert J Walker.jpg Robert J. Walker


 * - style="height:2em"
 * | Whig
 * rowspan=8 | Democratic
 * rowspan=8 | Democratic

! 7
 * - style="height:2em"
 * align=left | JFTrotter.jpg James F. Trotter
 * | Democratic
 * nowrap | Jan 22, 1838 – Jul 10, 1838
 * Appointed to continue Black's term.Resigned.


 * - style="height:2em"
 * colspan=3 | Vacant
 * nowrap | Jul 10, 1838 – Nov 12, 1838

! 8
 * - style="height:2em"
 * align=left | Thomas H. Williams
 * | Democratic
 * nowrap | Nov 12, 1838 – Mar 4, 1839
 * Appointed to continue Black's term.Elected in 1839 to finish Black's term..

! rowspan=3 | 9
 * - style="height:2em"
 * rowspan=3 align=left | JHenderson.jpg John Henderson
 * rowspan=3 | Whig
 * rowspan=3 nowrap | Mar 4, 1839 – Mar 4, 1845
 * rowspan=3 | Elected in 1838..
 * rowspan=3 | 5


 * - style="height:2em"
 * rowspan=5 | 5
 * rowspan=3 | Re-elected in 1841.Resigned to become U.S. Secretary of the Treasury.
 * rowspan=3 | Re-elected in 1841.Resigned to become U.S. Secretary of the Treasury.


 * - style="height:2em"

! rowspan=4 | 10
 * - style="height:2em"
 * rowspan=4 align=left | JSpeight2.jpg Jesse Speight
 * rowspan=4 | Democratic
 * rowspan=4 nowrap | Mar 4, 1845 – May 1, 1847
 * rowspan=4 | Elected in 1844.Died.
 * rowspan=7 | 6


 * - style="height:2em"
 * nowrap | Mar 5, 1845 – Nov 3, 1845
 * colspan=3 | Vacant
 * colspan=3 | Vacant

! 6
 * - style="height:2em"
 * Appointed to continue Walker's term.Elected in 1846 to finish Walker's term..
 * nowrap | Nov 3, 1845 – Mar 4, 1847
 * | Democratic
 * align=right | Joseph W. Chalmers

! rowspan=7 | 7
 * - style="height:2em"
 * rowspan=10 | 6
 * rowspan=7 | Elected in 1846 or 1847.Resigned to become Governor of Mississippi.
 * rowspan=7 nowrap | Mar 4, 1847 – Jan 8, 1852
 * rowspan=7 | Democratic
 * rowspan=7 align=right | HSFoote.jpg Henry S. Foote
 * rowspan=7 align=right | HSFoote.jpg Henry S. Foote


 * - style="height:2em"
 * colspan=3 | Vacant
 * nowrap | May 1, 1847 – Aug 10, 1847

! rowspan=3 | 11
 * - style="height:2em"
 * rowspan=3 align=left | President-Jefferson-Davis.jpg Jefferson Davis
 * rowspan=3 | Democratic
 * rowspan=3 nowrap | Aug 10, 1847 – Sep 23, 1851
 * rowspan=2 | Appointed to continue Speight's term.Elected in 1848 to finish Speight's term.


 * - style="height:2em"


 * - style="height:2em"
 * Re-elected in 1850.Resigned to run for Governor of Mississippi.
 * rowspan=9 | 7


 * - style="height:2em"
 * colspan=3 | Vacant
 * nowrap | Sep 23, 1851 – Dec 1, 1851

! rowspan=3 | 12
 * - style="height:2em"
 * rowspan=3 align=left | John Jones McRae.jpg John J. McRae
 * rowspan=3 | Democratic
 * rowspan=3 nowrap | Dec 1, 1851 – Mar 17, 1852
 * rowspan=3 | Appointed to continue Davis's term.Successor elected.


 * - style="height:2em"
 * nowrap | Jan 8, 1852 – Feb 18, 1852
 * colspan=3 | Vacant
 * colspan=3 | Vacant

! rowspan=2 | 8
 * - style="height:2em"
 * rowspan=2 | Elected to finish Foote's term.Retired.
 * rowspan=2 nowrap | Feb 18, 1852 – Mar 4, 1853
 * rowspan=2 | Whig
 * rowspan=2 align=right | WBrooke.jpg Walker Brooke

! rowspan=4 | 13
 * - style="height:2em"
 * rowspan=4 align=left | Stephen Adams.jpg Stephen Adams
 * rowspan=4 | Democratic
 * rowspan=4 nowrap | Mar 17, 1852 – Mar 4, 1857
 * rowspan=4 | Elected to finish Davis's term..


 * - style="height:2em"
 * rowspan=4 | 7
 * nowrap | Mar 4, 1853 – Jan 7, 1854
 * colspan=3 | Vacant
 * nowrap | Mar 4, 1853 – Jan 7, 1854
 * colspan=3 | Vacant

! rowspan=4 | 9
 * - style="height:2em"
 * rowspan=3 | Elected late in 1854
 * rowspan=4 nowrap | Jan 7, 1854 – Jan 12, 1861
 * rowspan=4 | Democratic
 * rowspan=4 align=right | Hon. Brown - NARA - 528693.jpg Albert G. Brown


 * - style="height:2em"

! rowspan=3 | 14
 * - style="height:2em"
 * rowspan=3 align=left | President-Jefferson-Davis.jpg Jefferson Davis
 * rowspan=3 | Democratic
 * rowspan=3 nowrap | Mar 4, 1857 – Jan 21, 1861
 * rowspan=3 | Elected in 1856 or 1857.Resigned.
 * rowspan=5 | 8


 * - style="height:2em"
 * rowspan=5 | 8
 * Re-elected in 1859.Withdrew.
 * Re-elected in 1859.Withdrew.


 * - style="height:2em"
 * rowspan=7 | Civil War and Reconstruction
 * rowspan=7 nowrap | Jan 12, 1861 – Feb 23, 1870
 * rowspan=7 colspan=3 | Vacant


 * - style="height:2em"
 * rowspan=6 colspan=3 | Vacant
 * rowspan=6 nowrap | Jan 21, 1861 – Feb 23, 1870
 * rowspan=6 | Civil War and Reconstruction


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=3 | 9


 * - style="height:2em"
 * rowspan=4 | 9
 * rowspan=4 | 9


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=6 | 10

! rowspan=4 | 15 ! 10
 * - style="height:2em"
 * rowspan=4 align=left | SenAdelbertAmes LOC A000172.jpg Adelbert Ames
 * rowspan=4 | Republican
 * rowspan=4 nowrap | Feb 23, 1870 – Jan 4, 1874
 * rowspan=4 | Elected in 1870 upon readmission.Resigned to become Governor of Mississippi.
 * Elected in 1870 upon readmission..
 * nowrap | Feb 23, 1870 – Mar 4, 1871
 * | Republican
 * align=right | Hiram_Rhodes_Revels_-_Brady-Handy-(restored).png Hiram R. Revels


 * - style="height:2em"
 * rowspan=6 | 10
 * nowrap | Mar 4, 1871 – Dec 1, 1871
 * colspan=3 | Vacant
 * nowrap | Mar 4, 1871 – Dec 1, 1871
 * colspan=3 | Vacant

! rowspan=5 | 11
 * - style="height:2em"
 * rowspan=5 | Elected in 1870, but remained Governor until Dec 1871..
 * rowspan=5 nowrap | Dec 1, 1871 – Mar 4, 1877
 * rowspan=5 | Republican
 * rowspan=5 align=right | JLAlcorn.jpg James L. Alcorn


 * - style="height:2em"


 * - style="height:2em"
 * colspan=3 | Vacant
 * nowrap | Jan 4, 1874 – Feb 3, 1874

! 16
 * - style="height:2em"
 * align=left | HRPease.jpg Henry R. Pease
 * | Republican
 * nowrap | Feb 3, 1874 – Mar 4, 1875
 * Elected to finish Ames's term.Retired.

! rowspan=3 | 17
 * - style="height:2em"
 * rowspan=3 align=left | Blanche Bruce - Brady-Handy.jpg Blanche Bruce
 * rowspan=3 | Republican
 * rowspan=3 nowrap | Mar 4, 1875 – Mar 4, 1881
 * rowspan=3 | Elected in 1874..
 * rowspan=3 | 11

! rowspan=5 | 12
 * - style="height:2em"
 * rowspan=3 | 11
 * rowspan=3 | Elected in 1876.
 * rowspan=5 nowrap | Mar 4, 1877 – Mar 6, 1885
 * rowspan=5 | Democratic
 * rowspan=5 align=right | Lucius Quintus Cincinnatus Lamar II - Brady-Handy.jpg Lucius Q. C. Lamar
 * rowspan=5 align=right | Lucius Quintus Cincinnatus Lamar II - Brady-Handy.jpg Lucius Q. C. Lamar


 * - style="height:2em"

! rowspan=13 | 18
 * - style="height:2em"
 * rowspan=13 align=left | James Zachariah George.jpg James Z. George
 * rowspan=13 | Democratic
 * rowspan=13 nowrap | Mar 4, 1881 – Aug 14, 1897
 * rowspan=5 | Elected in 1880.
 * rowspan=5 | 12


 * - style="height:2em"
 * rowspan=5 | 12
 * rowspan=2 | Re-elected in 1883.Resigned.
 * rowspan=2 | Re-elected in 1883.Resigned.


 * - style="height:2em"


 * - style="height:2em"
 * nowrap | Mar 6, 1885 – Mar 9, 1885
 * colspan=3 | Vacant
 * colspan=3 | Vacant

! rowspan=5 | 13
 * - style="height:2em"
 * rowspan=2 | Appointed to continue Lamar's term.Elected in 1886 to finish Lamar's term.
 * rowspan=5 nowrap | Mar 9, 1885 – Jan 24, 1894
 * rowspan=5 | Democratic
 * rowspan=5 align=right | ECWalthall.jpg Edward C. Walthall


 * - style="height:2em"
 * rowspan=3 | Re-elected in 1886.
 * rowspan=3 | 13


 * - style="height:2em"
 * rowspan=5 | 13
 * rowspan=3 | Re-elected in 1889.Resigned.
 * rowspan=3 | Re-elected in 1889.Resigned.


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=5 | Re-elected in 1892. Died.
 * rowspan=9 | 14


 * - style="height:2em"
 * nowrap | Jan 24, 1894 – Feb 7, 1894
 * colspan=3 | Vacant
 * colspan=3 | Vacant

! 14
 * - style="height:2em"
 * Elected to finish Walthall's term..
 * nowrap | Feb 7, 1894 – Mar 4, 1895
 * | Democratic
 * align=right | AnselmJMcLaurin.jpg Anselm J. McLaurin

! rowspan=4 | 15
 * - style="height:2em"
 * rowspan=7 | 14
 * rowspan=4 | Elected early in 1892. Died.
 * rowspan=4 nowrap | Mar 4, 1895 – Apr 21, 1898
 * rowspan=4 | Democratic
 * rowspan=4 align=right | ECWalthall.jpg Edward C. Walthall
 * rowspan=4 align=right | ECWalthall.jpg Edward C. Walthall


 * - style="height:2em"


 * - style="height:2em"
 * colspan=3 | Vacant
 * nowrap | Aug 14, 1897 – Oct 8, 1897

! rowspan=12 | 19
 * - style="height:2em"
 * rowspan=12 align=left | Hernando Money - Brady-Handy.jpg Hernando Money
 * rowspan=12 | Democratic
 * rowspan=12 nowrap | Oct 8, 1897 – Mar 4, 1911
 * rowspan=3 | Appointed to finish George's term.


 * - style="height:2em"
 * nowrap | Apr 21, 1898 – May 31, 1898
 * colspan=3 | Vacant
 * colspan=3 | Vacant

! rowspan=2 | 16
 * - style="height:2em"
 * rowspan=2 | Appointed to continue Walthall's term.Elected in 1900 to finish Walthall's term.Retired.
 * rowspan=2 nowrap | May 31, 1898 – Mar 4, 1901
 * rowspan=2 | Democratic
 * rowspan=2 align=right | William V Sullivan.jpg William V. Sullivan


 * - style="height:2em"
 * rowspan=3 | Elected to full term in 1899.
 * rowspan=3 | 15

! rowspan=5 | 17
 * - style="height:2em"
 * rowspan=3 | 15
 * rowspan=3 | Elected in 1900.
 * rowspan=5 nowrap | Mar 4, 1901 – Dec 22, 1909
 * rowspan=5 | Democratic
 * rowspan=5 align=right | AnselmJMcLaurin.jpg Anselm J. McLaurin
 * rowspan=5 align=right | AnselmJMcLaurin.jpg Anselm J. McLaurin


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=6 | Re-elected in 1904. Retired.
 * rowspan=6 | 16


 * - style="height:2em"
 * rowspan=6 | 16
 * rowspan=2 | Re-elected early in 1904. Died.
 * rowspan=2 | Re-elected early in 1904. Died.


 * - style="height:2em"


 * - style="height:2em"
 * nowrap | Dec 22, 1909 – Dec 27, 1909
 * colspan=3 | Vacant
 * colspan=3 | Vacant

! 18
 * - style="height:2em"
 * Appointed to continue McLaurin's term.Successor qualified.
 * nowrap | Dec 27, 1909 – Feb 22, 1910
 * | Democratic
 * align=right | James Gordon.jpg James Gordon

! rowspan=2 | 19
 * - style="height:2em"
 * rowspan=2 | Elected to finish McLaurin's term.Lost nomination to full term.
 * rowspan=2 nowrap | Feb 23, 1910 – Mar 4, 1913
 * rowspan=2 | Democratic
 * rowspan=2 align=right | LeRoy Percy, bw photo portrait, circa 1910.jpg LeRoy Percy

! rowspan=6 | 20
 * - style="height:2em"
 * rowspan=6 align=left | John Sharp Williams.jpg John Sharp Williams
 * rowspan=6 | Democratic
 * rowspan=6 nowrap | Mar 4, 1911 – Mar 4, 1923
 * rowspan=3 | Elected early in 1908.
 * rowspan=3 | 17

! rowspan=3 | 20
 * - style="height:2em"
 * rowspan=3 | 17
 * rowspan=3 | Elected in 1912.Lost renomination.
 * rowspan=3 nowrap | Mar 4, 1913 – Mar 4, 1919
 * rowspan=3 | Democratic
 * rowspan=3 align=right | James K. Vardaman Sr. (1905).jpg James K. Vardaman
 * rowspan=3 align=right | James K. Vardaman Sr. (1905).jpg James K. Vardaman


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=3 | Re-elected in 1916.Retired.
 * rowspan=3 | 18

! rowspan=12 | 21
 * - style="height:2em"
 * rowspan=3 | 18
 * rowspan=3 | Elected in 1918.
 * rowspan=12 nowrap | Mar 4, 1919 – Jun 22, 1941
 * rowspan=12 | Democratic
 * rowspan=12 align=right | PatHarrison.jpg Pat Harrison
 * rowspan=12 align=right | PatHarrison.jpg Pat Harrison


 * - style="height:2em"

! rowspan=6 | 21
 * - style="height:2em"
 * rowspan=6 align=left | HubertDStephens.jpg Hubert D. Stephens
 * rowspan=6 | Democratic
 * rowspan=6 nowrap | Mar 4, 1923 – Jan 3, 1935
 * rowspan=3 | Elected in 1922.
 * rowspan=3 | 19


 * - style="height:2em"
 * rowspan=3 | 19
 * rowspan=3 | Re-elected in 1924.
 * rowspan=3 | Re-elected in 1924.


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=3 | Re-elected in 1928.Lost renomination.
 * rowspan=3 | 20


 * - style="height:2em"
 * rowspan=3 | 20
 * rowspan=3 | Re-elected in 1930.
 * rowspan=3 | Re-elected in 1930.


 * - style="height:2em"

! rowspan=10 | 22
 * - style="height:2em"
 * rowspan=10 align=left | TheodoreBilbo.jpg Theodore G. Bilbo
 * rowspan=10 | Democratic
 * rowspan=10 nowrap | Jan 3, 1935 – Aug 21, 1947
 * rowspan=3 | Elected in 1934.
 * rowspan=3 | 21


 * - style="height:2em"
 * rowspan=6 | 21
 * rowspan=3 | Re-elected in 1936.Died.
 * rowspan=3 | Re-elected in 1936.Died.


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=6 | Re-elected in 1940.
 * rowspan=6 | 22


 * - style="height:2em"
 * nowrap | Jun 22, 1941 – Jun 30, 1941
 * colspan=3 | Vacant
 * colspan=3 | Vacant

! 22
 * - style="height:2em"
 * Appointed to continue Harrison's term.Retired when successor elected.
 * nowrap | Jun 30, 1941 – Sep 28, 1941
 * | Democratic
 * align=right | James O Eastland.jpg James Eastland

! 23
 * - style="height:2em"
 * Elected to finish Harrison's term.Lost renomination.
 * nowrap | Sep 29, 1941 – Jan 3, 1943
 * | Democratic
 * align=right | U.S. Senator Wall Doxey (D-MS).jpg Wall Doxey

! rowspan=20 | 24
 * - style="height:2em"
 * rowspan=5 | 22
 * rowspan=5 | Elected in 1942.
 * rowspan=20 nowrap | Jan 3, 1943 – Dec 27, 1978
 * rowspan=20 | Democratic
 * rowspan=20 align=right | James O Eastland.jpg James Eastland
 * rowspan=20 align=right | James O Eastland.jpg James Eastland


 * - style="height:2em"


 * - style="height:2em"
 * Re-elected in 1946.Died.
 * rowspan=5 | 23


 * - style="height:2em"
 * colspan=3 | Vacant
 * nowrap | Aug 21, 1947 – Nov 5, 1947

! rowspan=22 | 23
 * - style="height:2em"
 * rowspan=22 align=left | John Cornelius Stennis (cropped).jpg John C. Stennis
 * rowspan=22 | Democratic
 * rowspan=22 nowrap | Nov 5, 1947 – Jan 3, 1989
 * rowspan=3 | Elected to finish Bilbo's term.


 * - style="height:2em"
 * rowspan=3 | 23
 * rowspan=3 | Re-elected in 1948.
 * rowspan=3 | Re-elected in 1948.


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=3 | Re-elected in 1952.
 * rowspan=3 | 24


 * - style="height:2em"
 * rowspan=3 | 24
 * rowspan=3 | Re-elected in 1954.
 * rowspan=3 | Re-elected in 1954.


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=3 | Re-elected in 1958.
 * rowspan=3 | 25


 * - style="height:2em"
 * rowspan=3 | 25
 * rowspan=3 | Re-elected in 1960.
 * rowspan=3 | Re-elected in 1960.


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=3 | Re-elected in 1964.
 * rowspan=3 | 26


 * - style="height:2em"
 * rowspan=3 | 26
 * rowspan=3 | Re-elected in 1966.
 * rowspan=3 | Re-elected in 1966.


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=3 | Re-elected in 1970.
 * rowspan=3 | 27


 * - style="height:2em"
 * rowspan=4 | 27
 * rowspan=3 | Re-elected in 1972.Retired, and resigned early to give successor preferential seniority.
 * rowspan=3 | Re-elected in 1972.Retired, and resigned early to give successor preferential seniority.


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=4 | Re-elected in 1976.
 * rowspan=4 | 28

! rowspan=23 | 25
 * - style="height:2em"
 * Appointed early to finish Eastland's term, having already been elected to the next term.
 * rowspan=23 nowrap | Dec 27, 1978 – Apr 1, 2018
 * rowspan=23 | Republican
 * rowspan=23 align=right | Thad_Cochran_official_photo.jpg Thad Cochran


 * - style="height:2em"
 * rowspan=3 | 28
 * rowspan=3 | Elected in 1978.
 * rowspan=3 | Elected in 1978.


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=3 | Re-elected in 1982.Retired.
 * rowspan=3 | 29


 * - style="height:2em"
 * rowspan=3 | 29
 * rowspan=3 | Re-elected in 1984.
 * rowspan=3 | Re-elected in 1984.


 * - style="height:2em"

! rowspan=10 | 24
 * - style="height:2em"
 * rowspan=10 align=left | Trent Lott official portrait.jpg Trent Lott
 * rowspan=10 | Republican
 * rowspan=10 nowrap | Jan 3, 1989 – Dec 18, 2007
 * rowspan=3 | Elected in 1988.
 * rowspan=3 | 30


 * - style="height:2em"
 * rowspan=3 | 30
 * rowspan=3 | Re-elected in 1990.
 * rowspan=3 | Re-elected in 1990.


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=3 | Re-elected in 1994.
 * rowspan=3 | 31


 * - style="height:2em"
 * rowspan=3 | 31
 * rowspan=3 | Re-elected in 1996.
 * rowspan=3 | Re-elected in 1996.


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=3 | Re-elected in 2000.
 * rowspan=3 | 32


 * - style="height:2em"
 * rowspan=5 | 32
 * rowspan=5 | Re-elected in 2002.
 * rowspan=5 | Re-elected in 2002.


 * - style="height:2em"


 * - style="height:2em"
 * Re-elected in 2006.Resigned.
 * rowspan=5 | 33


 * - style="height:2em"
 * colspan=3 | Vacant
 * nowrap | Dec 18, 2007 – Dec 31, 2007

! rowspan=11 | 25
 * - style="height:2em"
 * rowspan=11 align=left | SenatorRogerWicker(R-MS).jpg Roger Wicker
 * rowspan=11 | Republican
 * rowspan=11 nowrap | Dec 31, 2007 – present
 * rowspan=3 | Appointed to continue Lott's term.Elected in 2008 to finish Lott's term.


 * - style="height:2em"
 * rowspan=3 | 33
 * rowspan=3 | Re-elected in 2008.
 * rowspan=3 | Re-elected in 2008.


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=5 | Re-elected in 2012.
 * rowspan=5 | 34


 * - style="height:2em"
 * rowspan=5 | 34
 * rowspan=2 | Re-elected in 2014.Resigned.
 * rowspan=2 | Re-elected in 2014.Resigned.


 * - style="height:2em"
 * rowspan=3


 * - style="height:2em"
 * nowrap | Apr 1, 2018 – Apr 2, 2018
 * colspan=3 | Vacant
 * colspan=3 | Vacant

! rowspan=5 | 26
 * - style="height:2em"
 * rowspan=2 | Appointed to continue Cochran's term.Elected in 2018 in runoff election to finish Cochran's term.
 * rowspan=5 nowrap | Apr 2, 2018 – present
 * rowspan=5 | Republican
 * rowspan=5 align=right | Cindy Hyde-Smith official photo (cropped).jpg Cindy Hyde-Smith


 * - style="height:2em"
 * rowspan=3 | Re-elected in 2018.
 * rowspan=3 | 35


 * - style="height:2em"
 * rowspan=3 | 35
 * rowspan=3 | Re-elected in 2020.
 * rowspan=3 | Re-elected in 2020.


 * - style="height:2em"


 * - style="height:2em"
 * rowspan=2 colspan=5 | To be determined in the 2024 election.
 * rowspan=2|36


 * - style="height:2em"
 * 36
 * colspan=5 | To be determined in the 2026 election.
 * colspan=5 | To be determined in the 2026 election.