2016–17 UC Sampdoria season

The 2016–17 season was Unione Calcio Sampdoria's 60th season in Serie A, and their 5th consecutive season in the top-flight. Sampdoria competed in Serie A, finishing 10th, and in the Coppa Italia, where the club was eliminated in the round of 16 by Roma.

Appearances and goals
! colspan=14 style=background:#dcdcdc; text-align:center| Goalkeepers

! colspan=14 style=background:#dcdcdc; text-align:center| Defenders

! colspan=14 style=background:#dcdcdc; text-align:center| Midfielders

! colspan=14 style=background:#dcdcdc; text-align:center| Forwards

! colspan=14 style=background:#dcdcdc; text-align:center| Players transferred out during the season

Goalscorers
Last updated: 28 May 2017

Clean sheets
Last updated: 28 May 2017

Disciplinary record
Last updated: 28 May 2017