2020–21 SS Lazio season

The 2020–21 season was the 120th season in the existence of S.S. Lazio and the club's 33rd consecutive season in the top flight of Italian football. In addition to the domestic league, Lazio participated in this season's editions of the Coppa Italia and also participated in the UEFA Champions League. The season covered the period from 2 August 2020 to 30 June 2021.

Matches
The league fixtures were announced on 2 September 2020.

Group stage
The group stage draw was held on 1 October 2020.

Round of 16
The draw for the round of 16 was held on 14 December 2020.

Appearances and goals
! colspan=14 style="background:#B2FFFF; text-align:center"| Goalkeepers

! colspan=14 style="background:#B2FFFF; text-align:center"| Defenders

! colspan=14 style="background:#B2FFFF; text-align:center"| Midfielders

! colspan=14 style="background:#B2FFFF; text-align:center"| Forwards

! colspan=14 style="background:#B2FFFF; text-align:center"| Players transferred out during the season