2021–22 in Italian football

The 2021–22 season was the 120th season of competitive football in Italy.

Promotions and relegations (pre-season)
Teams promoted to Serie A Teams relegated from Serie A
 * Empoli
 * Salernitana
 * Venezia
 * Benevento
 * Parma
 * Crotone

Teams promoted to Serie B
 * Como (Group A)
 * Perugia (Group B)
 * Ternana (Group C)
 * Alessandria (Play-Off Winner)

Teams relegated from Serie B
 * Chievo (excluded)
 * Reggiana
 * Pescara
 * Virtus Entella

Round of 16

 * }

Knockout round play-offs

 * }

Round of 16

 * }

Quarter-finals

 * }

Play-off round

 * }

Round of 16

 * }

Quarter-finals

 * }

Semi-finals

 * }

First round

 * }

Second round

 * }

Knockout round play-offs

 * }

Round of 16

 * }

Quarter-finals

 * }

Semi-finals

 * }

Semi-finals

 * }

Final

 * }

Round 2

 * }

Quarter-finals

 * }