2021–22 Sevilla FC season

The 2021–22 season was the 115th season in the existence of Sevilla and the club's 21st consecutive season in the top flight of Spanish football. In addition to the domestic league, Sevilla also participated in this season's editions of the Copa del Rey, the UEFA Champions League and the UEFA Europa League.

Players
As of 30 August 2021.

Matches
The league fixtures were announced on 30 June 2021.

Group stage
The draw for the group stage was held on 26 August 2021.

Knockout round play-offs
The knockout round play-offs draw was held on 13 December 2021.

Round of 16
The draw for the round of 16 was held on 25 February 2022.

Squad appearances and goals
! colspan=14 style=background:#dcdcdc; text-align:center|Goalkeepers

! colspan=14 style=background:#dcdcdc; text-align:center|Defenders

! colspan=14 style=background:#dcdcdc; text-align:center|Midfielders

! colspan=14 style=background:#dcdcdc; text-align:center|Forwards

! colspan=14 style=background:#dcdcdc; text-align:center|Players who have made an appearance this season but have left the club


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Disciplinary record
Includes all competitive matches.