2022 North Dakota State Bison football team

The 2022 North Dakota State Bison football team represented North Dakota State University as a member of the Missouri Valley Football Conference (MVFC) during the 2022 NCAA Division I FCS football season. The Bison were led by fourth-year head coach Matt Entz. They played their home games at the Fargodome in Fargo, North Dakota. The Bison finished their regular season with an overall record of 9–2 and 7–1 in MVFC play. NDSU received the number 3 overall seed in the FCS playoffs. The Bison then beat Montana in the second round, Samford in the quarterfinals, and Incarnate Word in the semifinals, before falling to topseed and archrival South Dakota State in the FCS National Championship. This was the program's first loss in the FCS title game, and only their third ever loss in a title game at any level.

2023 NFL Draft
The following Bison players were selected in the 2023 NFL Draft: