2006 Australian Open – Girls' singles

Anastasia Pavlyuchenkova won the title, defeating Caroline Wozniacki in the final, 1–6, 6–2, 6–3.

Victoria Azarenka was the defending champion, but chose to participate in the women's qualifying competition. She qualified for the main draw where she lost to 32nd seed Sania Mirza in the first round.

Seeds
• # Caroline Wozniacki (final)

• # 🇷🇴 Ioana Raluca Olaru (semifinals)

• # 🇸🇰 Dominika Cibulková (quarterfinals)

• # 🇯🇵 Ayumi Morita (semifinals)

• # 🇨🇦 Sharon Fichman (quarterfinals)

• # 🇰🇿 Amina Rakhim (quarterfinals)

• # 🇷🇴 Sorana Cîrstea (third round)

• # 🇷🇺 Anastasia Pavlyuchenkova (champion)

• # Bibiane Schoofs (second round, retired)

• # Anna Tatishvili (third round)

• # Marrit Boonstra (first round, retired)

• # 🇦🇹 Tamira Paszek (quarterfinals)

• # 🇨🇿 Nikola Fraňková (first round)

• # 🇷🇺 Evgeniya Rodina (second round)

• # 🇫🇷 Alizé Cornet (second round)

• # Timea Bacsinszky (third round)