2015 Western & Southern Open – Men's doubles

Bob and Mike Bryan were the two-time defending champions but lost in the quarterfinals to Daniel Nestor and Édouard Roger-Vasselin. Nestor and Roger-Vasselin went on to win the title, defeating Marcin Matkowski and Nenad Zimonjić in the final, 6–2, 6–2.

Seeds
All seeds receive a bye into the second round. • # 🇺🇸 Bob Bryan / 🇺🇸 Mike Bryan (quarterfinals)

• # Ivan Dodig / 🇧🇷 Marcelo Melo (semifinals)

• # Jean-Julien Rojer / 🇷🇴 Horia Tecău (quarterfinals)

• # 🇮🇹 Simone Bolelli / 🇮🇹 Fabio Fognini (second round)

• # 🇮🇳 Rohan Bopanna / 🇷🇴 Florin Mergea (quarterfinals)

• # 🇵🇱 Marcin Matkowski / 🇷🇸 Nenad Zimonjić (final)

• # 🇬🇧 Jamie Murray / 🇦🇺 John Peers (second round)

• # 🇨🇦 Vasek Pospisil / 🇺🇸 Jack Sock (second round)