2022 I.ČLTK Prague Open – Women's doubles

Anna Bondár and Kimberley Zimmermann were the defending champions, but chose not to participate.

Bárbara Gatica and Rebeca Pereira won the title, defeating Miriam Kolodziejová and Jesika Malečková in the final, 6–4, 6–2.

Seeds
• # Bárbara Gatica / 🇧🇷 Rebeca Pereira (champions)

• # 🇨🇿 Miriam Kolodziejová / 🇨🇿 Jesika Malečková (final)

• # 🇨🇿 Anastasia Dețiuc / 🇨🇿 Johana Marková (first round)

• # Despina Papamichail / 🇷🇸 Natalija Stevanović (first round, withdrew)