2022 Australian Open – Boys' singles

Bruno Kuzuhara defeated Jakub Menšík in the final, 7–6(7–4), 6–7(6–8), 7–5 to win the boys' singles title at the 2022 Australian Open.

Harold Mayot was the defending champion but was no longer eligible to participate in junior events. Mayot competed at the men's singles qualifying event, where he was defeated in the first round by Quentin Halys.

Seeds
• 🇺🇸 Bruno Kuzuhara (champion)

• Mili Poljičak (third round)

•  Adolfo Daniel Vallejo (semifinals)

• 🇨🇿 Jakub Menšík (final)

• 🇵🇪 Ignacio Buse (first round)

• 🇫🇷 Gabriel Debru (first round)

• 🇱🇹 Edas Butvilas (quarterfinals)

• 🇵🇱 Olaf Pieczkowski (second round)

• 🇲🇽 Rodrigo Pacheco Méndez (quarterfinals)

• 🇲🇰 Kalin Ivanovski (first round)

•  Kilian Feldbausch (semifinals)

• 🇭🇰 Coleman Wong (third round)

• 🇺🇸 Ozan Colak (quarterfinals)

•  Dino Prižmić (third round)

•  Bor Artnak (first round)

• 🇦🇷 Lautaro Midón (third round)

Seeds
• # 🇺🇸 Kurt Miller (qualifying competition)

• # 🇨🇿 Štěpán Mrůzek (first round)

• # 🇺🇸 Alex Michelsen (qualifying competition)

• # 🇬🇧 Louis Bowden (qualified)

• # 🇬🇧 Patrick Brady (first round)

• # 🇮🇹 Niccolò Ciavarella (qualifying competition)

• # 🇮🇹 Lorenzo Ferri (first round)

• # 🇮🇹 Gianmarco Gandolfi (qualified)

• # Daniël Verbeek (qualified)

• # 🇦🇷 Valentín Basel (first round)

• # Theodoros Mitsakos (qualifying competition)

• # 🇯🇵 Kenta Miyoshi (qualifying competition)

• # 🇺🇸 Quang Duong (qualified)

• # 🇳🇿 Jack Loutit (qualified)

• # Manfredi Graziani (first round)

• # 🇯🇵 Asahi Harazaki (qualified)

Qualifiers
• # 🇳🇿 Jack Loutit

• # 🇦🇺 Henry Lamchinniah

• # 🇯🇵 Asahi Harazaki

• # 🇬🇧 Louis Bowden

• # 🇺🇸 Rohan Murali

• # Daniël Verbeek

• # 🇺🇸 Quang Duong

• # 🇮🇹 Gianmarco Gandolfi