1950 Eastern Illinois Panthers football team

The 1950 Eastern Illinois Panthers football team represented Eastern Illinois State College (now known as Eastern Illinois University) as a member of the Interstate Intercollegiate Athletic Conference (IIAC) during the 1950 college football season. The team was led by fifth-year head coach Maynard O'Brien and played their home games at Lincoln Field in Charleston, Illinois. The Panthers finished the season with a 5–3 record overall and a 2–2 record in conference play, tying for third place in the IIAC.