2004 Eastern Illinois Panthers football team

The 2004 Eastern Illinois Panthers football team represented Eastern Illinois University as a member of the Ohio Valley Conference (OVC) during the 2004 NCAA Division I-AA football season. Led by 18th-year head coach Bob Spoo, the Panthers compiled an overall record of 5–6 with a mark of 4–4 in conference play, placing fourth in the OVC. Eastern Illinois played their home games at O'Brien Stadium in Charleston, Illinois.