1916 Holy Cross football team

The 1916 Holy Cross football team was an American football team that represented the College of the Holy Cross in the 1916 college football season.

In its third year under head coach Luke Kelly, the team compiled a 4–5 record. Raymond Lynch was the team captain. He replaced captain-elect Mark Devlin, who withdrew from the school before the season began.

Holy Cross played its home games at Fitton Field on the college campus in Worcester, Massachusetts.