1981 US Open – Men's doubles

The men's doubles tournament at the 1981 US Open was held on September 1–13, 1981 on the outdoor hard courts at the USTA National Tennis Center in New York City, United States. Heinz Günthardt and Peter McNamara forfeited the title to Peter Fleming and John McEnroe in the final.

Seeds
• # 🇺🇸 John McEnroe / 🇺🇸 Peter Fleming (champions)

• # Heinz Günthardt / 🇦🇺 Peter McNamara (final)

• # 🇲🇽 Raúl Ramírez / 🇺🇸 Van Winitsky (second round)

• # 🇺🇸 Marty Riessen / 🇺🇸 Sherwood Stewart (first round)

• # 🇺🇸 Bruce Manson / 🇺🇸 Brian Teacher (first round)

• # 🇺🇸 Fritz Buehning / 🇺🇸 Ferdi Taygan (semifinals)

• # Kevin Curren / 🇺🇸 Steve Denton (quarterfinals)

• # 🇺🇸 Victor Amaya / 🇺🇸 Hank Pfister (quarterfinals)

• # 🇵🇱 Wojciech Fibak / 🇺🇸 Stan Smith (first round)

• # 🇺🇸 Terry Moor / 🇺🇸 Eliot Teltscher (third round)

• # 🇺🇸 Tim Gullikson / Bernard Mitton (second round)

• # Johan Kriek /  Frew McMillan (first round)

• # 🇺🇸 Andrew Pattison / 🇺🇸 Butch Walts (first round)

• # 🇷🇴 Ilie Năstase / 🇮🇹 Adriano Panatta (first round)

• # Raymond Moore / 🇺🇸 Erik van Dillen (third round)

• # Eddie Edwards / 🇺🇸 Craig Edwards (first round)