2006 US Open – Men's doubles

For the 2006 US Open tennis tournament series, Bob and Mike Bryan were the defending champions, but lost in the third round to Leoš Friedl and Mikhail Youzhny.

Martin Damm and Leander Paes won the title, defeating Jonas Björkman and Max Mirnyi in the final, 6–7(5–7), 6–4, 6–3.

Seeds
• # 🇺🇸 Bob Bryan / 🇺🇸 Mike Bryan (third round)

• # 🇸🇪 Jonas Björkman / 🇧🇾 Max Mirnyi (final)

• # 🇧🇸 Mark Knowles / 🇨🇦 Daniel Nestor (third round)

• # 🇦🇺 Paul Hanley / Kevin Ullyett (semifinals)

• # 🇫🇷 Fabrice Santoro / 🇷🇸 Nenad Zimonjić (quarterfinals)

• # 🇨🇿 Martin Damm / 🇮🇳 Leander Paes (champions)

• # 🇮🇱 Jonathan Erlich / 🇮🇱 Andy Ram (third round)

• # 🇸🇪 Simon Aspelin / 🇦🇺 Todd Perry (second round)

• # 🇨🇿 Lukáš Dlouhý / 🇨🇿 Pavel Vízner (second round)

• # 🇵🇱 Mariusz Fyrstenberg / 🇵🇱 Marcin Matkowski (third round)

• # 🇦🇹 Julian Knowle / 🇦🇹 Jürgen Melzer (second round)

• # 🇦🇷 José Acasuso / 🇦🇷 Sebastián Prieto (first round)

• # 🇨🇿 František Čermák / 🇨🇿 Jaroslav Levinský (second round)

• # 🇦🇺 Wayne Arthurs / 🇺🇸 Justin Gimelstob (second round)

• # 🇦🇹 Oliver Marach / 🇨🇿 Cyril Suk (first round)

• # 🇩🇪 Michael Kohlmann / 🇩🇪 Alexander Waske (third round)