2021–22 AS Roma season

The 2021–22 season was A.S. Roma's 95th season in existence and the club's 70th consecutive season in the top flight of Italian football. In addition to the domestic league, Roma participated in this season's editions of the Coppa Italia and the inaugural edition of the UEFA Europa Conference League, winning the latter tournament for the club's first major trophy since the 2007–08 Coppa Italia.



The season began with José Mourinho at the helm after Roma announced last season that Paulo Fonseca would step down.

Matches
The league fixtures were announced on 14 July 2021.

Play-off round
The draw for the play-off round was held on 2 August.

Group stage
The draw for the group stage was held on 27 August 2021.

Round of 16
The round of 16 draw was held on 25 February 2022.

Quarter-finals
The draw for the quarter-finals was held on 18 March 2022.

Semi-finals
The draw for the semi-finals was held on 18 March 2022, after the quarter-final draw.

Appearances and goals
! colspan=14 style="background:#B21B1C; color:#FFD700; text-align:center"| Goalkeepers

! colspan=14 style="background:#B21B1C; color:#FFD700; text-align:center"| Defenders

! colspan=14 style="background:#B21B1C; color:#FFD700; text-align:center"| Midfielders

! colspan=14 style="background:#B21B1C; color:#FFD700; text-align:center"| Forwards

! colspan=14 style="background:#B21B1C; color:#FFD700; text-align:center"| Players transferred out during the season