2021–22 Inter Milan season

The 2021–22 season was the 114th season in the existence of Inter Milan and the club's 106th consecutive season in the top division of Italian football. In addition to the domestic league, Inter participated in this season's editions of the Coppa Italia, the Supercoppa Italiana and the UEFA Champions League, winning the former two tournaments.

Kits
Supplier: Nike / Sponsors: Socios.com (front) / Lenovo (back) / DigitalBits (sleeve)

Goalkeeper kits
 * Outfield players kits

First-team squad
Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.

Loans ended

 * Notes:

Matches
The league fixtures were announced on 14 July 2021.

Group stage
The draw for the group stage was held on 26 August 2021.

Round of 16
The draw for the round of 16 was held on 13 December 2021.

Appearances and goals
! colspan=14 style="background:#dcdcdc; text-align:center| Goalkeepers

! colspan=14 style="background:#dcdcdc; text-align:center| Defenders

! colspan=14 style="background:#dcdcdc; text-align:center| Midfielders

! colspan=14 style="background:#dcdcdc; text-align:center| Forwards

! colspan=14 style="background:#dcdcdc; text-align:center| Players transferred out during the season