ETS2

Protein C-ETS2 is a protein that in humans is encoded by the ETS2 gene. The protein encoded by this gene belongs to the ETS family of transcription factors. It has been found to play a key role in the development of inflammatory bowel disease.

Interactions
ETS2 has been shown to interact with:


 * C-jun,
 * Cyclin-dependent kinase 10,
 * ERG,
 * myb, and
 * ZMYND11.

Clinical signficance
ETS2 has been linked to a variety of diseases, including Takayasu's arteritis, inflammatory bowel disease, primary sclerosing cholangitis, and ankylosing spondylitis, all associated with a region on chromosome 21 at 21q22.