Class C GPCR

The class C G-protein-coupled receptors are a class of G-protein coupled receptors that include the metabotropic glutamate receptors  and several additional receptors.

Structurally they are composed of four elements; an N-terminal signal sequence; a large hydrophilic extracellular agonist-binding region containing several conserved cysteine residues which could be involved in disulphide bonds; a shorter region containing seven transmembrane domains; and a C-terminal cytoplasmic domain of variable length. This protein family includes metabotropic glutamate receptors, the extracellular calcium-sensing receptors, the gamma-amino-butyric acid (GABA) type B receptors, and the vomeronasal type-2 receptors.

Calcium-sensing receptor-related

 * extracellular calcium-sensing receptor-related
 * Calcium-sensing receptor
 * GPRC6A

GABAB receptors

 * GABAB receptor (gamma-aminobutyric acid)
 * GABAB receptor 1
 * GABAB receptor 2

Metabotropic glutamate receptors

 * Metabotropic glutamate receptors (mGluR)
 * mGluR1
 * mGluR2
 * mGluR3
 * mGluR4
 * mGluR5
 * mGluR6
 * mGluR7
 * mGluR8

RAIG

 * Retinoic acid-inducible orphan G protein-coupled receptors (RAIG)
 * RAIG1
 * RAIG2
 * RAIG3
 * RAIG4

Taste receptors

 * Taste receptor
 * Taste receptor, type 1, member 1
 * Taste receptor, type 1, member 2
 * Taste receptor, type 1, member 3

Orphan

 * Class C Orphan receptors
 * GPR158
 * GPR179
 * GPR156

Other

 * Bride of sevenless protein
 * Vomeronasal receptor, type 2