LPAR2

Lysophosphatidic acid receptor 2 also known as LPA2 is a protein that in humans is encoded by the LPAR2 gene. LPA2 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).

Function
This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins.

Interactions
LPAR2 has been shown to interact with TRIP6.

Evolution
=== Paralogues ===


 * LPAR1
 * LPAR3
 * S1PR1
 * S1PR5
 * S1PR4
 * S1PR2
 * S1PR3
 * GPR6
 * GPR3
 * GPR12
 * MC4R
 * MC5R
 * CNR1
 * MC3R
 * CNR2
 * MC1R
 * GPR119
 * MC2R