GPR6

G protein-coupled receptor 6, also known as GPR6, is a protein which in humans is encoded by the GPR6 gene.

Function
GPR6 is a member of the G protein-coupled receptor family of transmembrane receptors. It has been reported that GPR6 is both constitutively active but in addition is further activated by sphingosine-1-phosphate.

GPR6 up-regulates cyclic AMP levels and promotes neurite outgrowth.

Inverse Agonist

 * Cannabidiol

Paralogues to GPR6 gene
Source:


 * GPR3
 * GPR12
 * S1PR5
 * S1PR1
 * CNR1
 * S1PR2
 * LPAR2
 * CNR2
 * MC1R
 * S1PR3
 * S1PR4
 * GPR119
 * MC3R
 * MC4R
 * MC5R
 * LPAR1
 * LPAR3
 * MC2R