S1PR2

Sphingosine-1-phosphate receptor 2, also known as S1PR2 or S1P2, is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P).

Function
This protein participates in sphingosine 1-phosphate-induced cell proliferation, survival, and transcriptional activation. It has also been shown to interact with Nogo-A (RTN4), an neurite outgrowth inhibitor. S1PR2 is expressed in neuronal and vascular cells and is crucial for the migration and growth of developing and injured neuronal and vascular system.

Paralogues

 * S1PR1
 * S1PR3
 * S1PR5
 * S1PR4
 * LPAR2
 * LPAR1
 * LPAR3
 * CNR1
 * GPR6
 * MC3R
 * GPR12
 * GPR3
 * MC4R
 * MC1R
 * CNR2
 * MC5R
 * MC2R
 * GPR119