P2RY8

P2Y purinoceptor 8 is a protein that in humans is encoded by the P2RY8 gene.

Function
The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y.

Clinical relevance
Recurrent mutations in this gene have been associated to cases of diffuse large B-cell lymphoma.