2014 US Open – Men's singles

Marin Čilić defeated Kei Nishikori in the final, 6–3, 6–3, 6–3 to win the men's singles tennis title at the 2014 US Open. It was his first major title. Čilić became the second Croatian to win a major men's singles title after his coach Goran Ivanišević at the 2001 Wimbledon Championships.

Rafael Nadal was the reigning champion, but withdrew before the tournament due to a right wrist injury.

Nishikori became the first Japanese in the Open Era to reach a major semifinal and final, and the first since Jiro Sato at the 1933 French Championships.

The finalists defeated Roger Federer and Novak Djokovic in their respective semifinals, guaranteeing a new major champion, the first major final with a guaranteed first-time champion since the 2008 Australian Open and the first major final with two first-time finalists since the 2005 French Open. Nishikori and Čilić were also the two lowest-ranked seeds to reach the US Open final since 2002. Between the 2005 Australian Open and 2020 US Open, this was the only major final not to feature a member of the Big Four.

This marked the first US Open appearance for future champion Dominic Thiem; he lost in the fourth round to Tomáš Berdych.

Seeds
• 🇷🇸 Novak Djokovic (semifinals)

• Roger Federer (semifinals)

•  Stan Wawrinka (quarterfinals)

• 🇪🇸 David Ferrer (third round)

• 🇨🇦 Milos Raonic (fourth round)

• 🇨🇿 Tomáš Berdych (quarterfinals)

• 🇧🇬 Grigor Dimitrov (fourth round)

• 🇬🇧 Andy Murray (quarterfinals)

• 🇫🇷 Jo-Wilfried Tsonga (fourth round)

• 🇯🇵 Kei Nishikori (final)

•  Ernests Gulbis (second round)

• 🇫🇷 Richard Gasquet (third round)

• 🇺🇸 John Isner (third round)

•  Marin Čilić (champion)

• 🇮🇹 Fabio Fognini (second round)

• 🇪🇸 Tommy Robredo (fourth round)

• 🇪🇸 Roberto Bautista Agut (fourth round)

•  Kevin Anderson (third round)

• 🇪🇸 Feliciano López (third round)

• 🇫🇷 Gaël Monfils (quarterfinals)

• 🇷🇺 Mikhail Youzhny (first round)

• 🇩🇪 Philipp Kohlschreiber (fourth round)

• 🇦🇷 Leonardo Mayer (third round)

• 🇫🇷 Julien Benneteau (first round)

•  Ivo Karlović (second round)

• 🇫🇷 Gilles Simon (fourth round)

• 🇨🇴 Santiago Giraldo (first round)

• 🇪🇸 Guillermo García-López (second round)

• 🇨🇿 Lukáš Rosol (first round)

• 🇫🇷 Jérémy Chardy (second round)

• 🇪🇸 Fernando Verdasco (second round)

•  João Sousa (second round)